Kumar D, Pfeffer J, Wingate D L
Gastrointestinal Science Research Unit, London Hospital, UK.
Digestion. 1990;45(2):80-7. doi: 10.1159/000200227.
Our study was designed to test the hypothesis that psychoneurosis in irritable bowel syndrome (IBS) may be the secondary effects of the unsatisfactory nature of the medical transactions (diagnosis, explanation, prognosis, and therapy) in IBS rather than a primary cause of the syndrome. We carried out psychometric assessments on three groups of subjects: 10 healthy volunteers, 12 patients diagnosed as suffering from benign gastrointestinal disease, and 18 patients with IBS. We found a significantly raised incidence of psychoneurosis in IBS, but the components of this were predominantly anxiety and obsession; the incidence of depression in all 3 groups was similar. We argue that the data support our hypothesis that the psychoneurotic manifestations are secondary components of IBS; the data do not support the hypothesis that IBS is a manifestation of depression.
我们的研究旨在检验这样一个假设，即肠易激综合征（IBS）中的神经症可能是IBS医疗过程（诊断、解释、预后和治疗）不尽人意的性质所产生的继发效应，而非该综合征的主要病因。我们对三组受试者进行了心理测量评估：10名健康志愿者、12名被诊断患有良性胃肠道疾病的患者以及18名IBS患者。我们发现IBS患者中神经症的发病率显著升高，但其主要成分是焦虑和强迫观念；所有三组中抑郁症的发病率相似。我们认为这些数据支持了我们的假设，即神经症表现是IBS的继发组成部分；这些数据不支持IBS是抑郁症表现的假设。
