Klasnja Aleksandar V, Jakovljevic Djordje G, Barak Otto F, Popadic Gacesa Jelena Z, Lukac Damir D, Grujic Nikola G
Department of Physiology, Medical faculty, University of Novi Sad, Novi Sad, Serbia.
Clin Physiol Funct Imaging. 2013 May;33(3):201-5. doi: 10.1111/cpf.12013. Epub 2012 Dec 13.
Cardiac power output (CPO) is an integrative measure of overall cardiac function as it accounts for both, flow- and pressure-generating capacities of the heart. The purpose of the present study was twofold: (i) to assess cardiac power output and its response to exercise in athletes and non-athletes and (ii) to determine the relationship between cardiac power output and reserve and selected measures of cardiac function and structure. Twenty male athletes and 32 age- and gender-matched healthy sedentary controls participated in this study. CPO was calculated as the product of cardiac output and mean arterial pressure, expressed in watts. Measures of hemodynamic status, cardiac structure and pumping capability were assessed by echocardiography. CPO was assessed at rest and after peak bicycle exercise. At rest, the two groups had similar values of cardiac power output (1·08 ± 0·2 W versus 1·1 ± 0·24 W, P>0·05), but the athletes demonstrated lower systolic blood pressure (109·5 ± 6·2 mmHg versus 117·2 ± 8·2 mmHg, P<0·05) and thicker posterior wall of the left ventricle (9·8 ± 1 mm versus 9 ± 1·1 mm, P<0·05). Peak CPO was higher in athletes (5·87 ± 0·75 W versus 5·4 ± 0·69 W, P<0·05) as was cardiac reserve (4·92 ± 0·66 W versus 4·26 ± 0·61 W, P<0·05), respectively. Peak exercise CPO and reserve were only moderately correlated with end-diastolic volume (r = 0·54; r = 0·46, P<0·05) and end-diastolic left ventricular internal diameter (r = 0·48; r = 0·42, P<0·05), respectively. Athletes demonstrated greater maximal cardiac pumping capability and reserve than non-athletes. The study provides new evidence that resting measures of cardiac structure and function need to be considered with caution in interpretation of maximal cardiac performance.
心脏功率输出（CPO）是对整体心脏功能的一种综合测量，因为它兼顾了心脏的流量生成能力和压力生成能力。本研究的目的有两个：（i）评估运动员和非运动员的心脏功率输出及其对运动的反应；（ii）确定心脏功率输出和储备与心脏功能和结构的选定测量指标之间的关系。20名男性运动员和32名年龄及性别匹配的健康久坐对照者参与了本研究。CPO通过心输出量与平均动脉压的乘积计算得出，以瓦特为单位表示。通过超声心动图评估血流动力学状态、心脏结构和泵血能力的测量指标。在静息状态和自行车运动峰值后评估CPO。静息时，两组的心脏功率输出值相似（1.08±0.2瓦对1.1±0.24瓦，P>0.05），但运动员的收缩压较低（109.5±6.2毫米汞柱对117.2±8.2毫米汞柱，P<0.05），左心室后壁更厚（9.8±1毫米对9±1.1毫米，P<0.05）。运动员的峰值CPO更高（5.87±0.75瓦对5.4±0.69瓦，P<0.05），心脏储备也更高（4.92±0.66瓦对4.26±0.61瓦，P<0.05）。运动峰值CPO和储备分别仅与舒张末期容积（r = 0.54；r = 0.46，P<0.05）和舒张末期左心室内径（r = 0.48；r = 0.42，P<0.05）中度相关。运动员表现出比非运动员更大的最大心脏泵血能力和储备。该研究提供了新的证据，即在解释最大心脏性能时，需要谨慎考虑心脏结构和功能的静息测量指标。
