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微创经椎间孔腰椎椎体间融合术后聚醚醚酮椎间融合器下沉

Subsidence of polyetheretherketone cage after minimally invasive transforaminal lumbar interbody fusion.

作者信息

Kim Moon-Chan, Chung Hung-Tae, Cho Jae-Lim, Kim Dong-Jun, Chung Nam-Su

机构信息

Department of Orthopaedic Surgery, Bumin Hospital, Busan, Korea.

出版信息

J Spinal Disord Tech. 2013 Apr;26(2):87-92. doi: 10.1097/BSD.0b013e318237b9b1.

DOI:10.1097/BSD.0b013e318237b9b1
PMID:23529151
Abstract

STUDY DESIGN

A retrospective case series.

OBJECTIVE

The aim of this study was to determine the rate of cage subsidence after minimally invasive transforaminal lumbar interbody fusion (MITLIF) conducted using a polyetheretherketone (PEEK) cage, and to identify associated risk factors.

SUMMARY OF BACKGROUND DATA

Although various rates of cage subsidence after lumbar interbody fusion have been reported, few studies have addressed subsidence rate after MITLIF using PEEK cage.

METHODS

A total of 104 consecutive patients who had undergone MITLIF using a PEEK cage with a minimum follow-up of 2 years were included in this study. Cage subsidence was defined to have occurred when a cage was observed to sink into an adjacent vertebral body by ≥2 mm on the postoperative or serial follow-up lateral radiographs. The demographic variables considered to affect cage subsidence were the following: age, sex, body mass index, bone mineral density, diagnosis, number of fusion segment, and the quality/quantity of back muscle, and the cage-related variables considered were: level of fusion, intervertebral angle, cage size, cage position, and postoperative distraction of disc height. Logistic regression analysis was conducted to explore relations between these variables and cage subsidence.

RESULTS

: For the 122 cages inserted, the rate of cage subsidence was 14.8% (18 cages), and cage subsidence occurred within 7.2±8.5 (1-25) months of surgery. The odds ratios for factors found to significantly increase the risk of cage subsidence were; 1.950 (95% confidence interval, 1.002-4.224) for L5-S1 level, and 1.018 (95% confidence interval, 1.000-1.066) for anterior cage position.

CONCLUSIONS

The rate of PEEK cage subsidence after MITLIF was relatively low. End-plate manipulation and cage insertion during MITLIF were not influenced by a small operation window.

摘要

研究设计

回顾性病例系列研究。

目的

本研究旨在确定使用聚醚醚酮(PEEK)椎间融合器进行微创经椎间孔腰椎椎间融合术(MITLIF)后椎间融合器下沉率,并确定相关危险因素。

背景数据总结

尽管已有报道腰椎椎间融合术后椎间融合器下沉率各异,但很少有研究涉及使用PEEK椎间融合器的MITLIF术后下沉率。

方法

本研究纳入了104例连续接受使用PEEK椎间融合器的MITLIF且至少随访2年的患者。椎间融合器下沉定义为在术后或系列随访的侧位X线片上观察到椎间融合器下沉至相邻椎体≥2mm。考虑的影响椎间融合器下沉的人口统计学变量如下:年龄、性别、体重指数、骨密度、诊断、融合节段数以及背部肌肉的质量/数量,考虑的与椎间融合器相关的变量有:融合节段水平、椎间角度、椎间融合器尺寸、椎间融合器位置以及术后椎间盘高度撑开情况。进行逻辑回归分析以探讨这些变量与椎间融合器下沉之间的关系。

结果

对于植入的122个椎间融合器,椎间融合器下沉率为14.8%(18个椎间融合器),且椎间融合器下沉发生在术后7.2±8.5(1 - 25)个月内。发现显著增加椎间融合器下沉风险的因素的比值比为:L5 - S1节段为1.950(95%置信区间,1.002 - 4.224),椎间融合器位于前方位置为1.018(95%置信区间,1.000 - 1.066)。

结论

MITLIF术后PEEK椎间融合器下沉率相对较低。MITLIF期间的终板操作和椎间融合器植入不受小手术窗口的影响。

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