School of Nursing, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, Republic of Korea.
Heart Lung. 2013 May-Jun;42(3):163-70. doi: 10.1016/j.hrtlng.2012.07.004. Epub 2013 Mar 25.
Little is known about frailty in people with chronic obstructive pulmonary disease (COPD). The purposes of this study were to describe frailty, to identify, which demographic and clinical characteristics contributed to frailty, and to examine the relationship between frailty and health-related outcomes in people with COPD.
This was a secondary cross-sectional study, using data from the National Health and Nutrition Evaluation Survey. The frailty index and outcome measures were derived primarily from survey responses.
The prevalence of frailty was 57.8%. Multivariate logistic regression showed that individuals with COPD who had self-reported shortness of breath and comorbid diabetes were more likely to be frail than those who did not. Frail people tended to have a greater number of disabilities.
The findings support the importance of frailty in the COPD population. Further study is needed to understand frailty in people with COPD, using objective measures for criteria of frailty.
人们对慢性阻塞性肺疾病（COPD）患者的虚弱知之甚少。本研究的目的是描述虚弱，确定哪些人口统计学和临床特征导致虚弱，并研究 COPD 患者虚弱与健康相关结局之间的关系。
这是一项使用全国健康和营养调查数据的二次横断面研究。衰弱指数和结局指标主要来自调查应答。
虚弱的患病率为 57.8%。多变量逻辑回归显示，与没有报告呼吸急促和合并糖尿病的 COPD 患者相比，有报告呼吸急促和合并糖尿病的 COPD 患者更有可能虚弱。虚弱的人往往有更多的残疾。
这些发现支持了虚弱在 COPD 人群中的重要性。需要进一步研究，使用客观的虚弱标准来了解 COPD 患者的虚弱情况。
