Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Institute of Health & Science Convergence, Chungbuk National University, Cheongju, South Korea.
Sci Rep. 2023 Aug 14;13(1):13205. doi: 10.1038/s41598-023-39319-8.
Few studies have examined the association between disability and chronic obstructive pulmonary disease (COPD). We compared the trends in the annual COPD prevalence between people with and without disabilities, and examined the association between disability and COPD. We linked the National Health Information Database (2008-2017) with the National Disability Registration Database, which includes more than 2 million people with disabilities every year. In the 2017 dataset, people with disabilities had a higher prevalence of COPD than those without disabilities (30.6% vs. 12.5%, P < 0.001). The age-standardized prevalence rate of COPD among people without disabilities increased from 4.2 in 2008 to 10.9% in 2017 (change of 6.7%), whereas that among those with disabilities increased from 7.0 to 17.1% (change of 10.1%). In multivariate analysis, compared to people without disabilities, those with disabilities had a higher probability of having COPD (adjusted odds ratio, 1.42; 95% confidence interval 1.42-1.43). The results of subgroup analysis by disability characteristics suggested that disabilities due to failure of an organ, such as the kidney, lung, heart, or liver, and severe disabilities were particularly vulnerable to COPD. In conclusion, people with disabilities are more likely to have COPD compared to people without disabilities. Further longitudinal studies that examine cause-and-effect relationship between disability and COPD are needed to clarify this relationship and to further investigate any potential negative effects associated with the coexistence of these conditions.
很少有研究探讨残疾与慢性阻塞性肺疾病（COPD）之间的关联。我们比较了有残疾和无残疾人群中 COPD 年患病率的趋势，并研究了残疾与 COPD 之间的关联。我们将国家健康信息数据库（2008-2017 年）与国家残疾登记数据库相链接，该数据库每年包含超过 200 万残疾人。在 2017 年的数据集中，有残疾的人比没有残疾的人 COPD 患病率更高（30.6%比 12.5%，P<0.001）。无残疾者的 COPD 年龄标准化患病率从 2008 年的 4.2%增加到 2017 年的 10.9%（变化 6.7%），而残疾者的 COPD 患病率从 7.0%增加到 17.1%（变化 10.1%）。在多变量分析中，与无残疾者相比，有残疾者患有 COPD 的可能性更高（调整后的优势比，1.42；95%置信区间 1.42-1.43）。按残疾特征进行的亚组分析结果表明，由于肾脏、肺、心脏或肝脏等器官衰竭以及严重残疾等原因导致的残疾尤其容易患 COPD。总之，与无残疾者相比，有残疾者更易患 COPD。需要进一步进行纵向研究，以阐明残疾与 COPD 之间的因果关系，并进一步研究这些疾病同时存在可能带来的任何负面影响。
