World J Gastroenterol. 2013 Mar 14;19(10):1505-7. doi: 10.3748/wjg.v19.i10.1505.
The role of alcohol in causing or aggravating the pathogenesis of inflammatory bowel disease is unclear. For finding a conclusive answer for this valuable question we conducted this review. Only two studies were identified that successfully fulfilled our inclusive criteria. Usual consumption of alcohol reduced the risk compared with less frequent use (odds ratio = 0.57, 95%CI: 0.37-0.86). Light alcoholic drinking has protective effects against development of ulcerative colitis. But this inverse association disappeared when smoking was included.
酒精在引发或加重炎症性肠病的发病机制中的作用尚不清楚。为了找到这个有价值的问题的明确答案,我们进行了这项综述。只有两项研究符合我们的纳入标准。与不频繁饮酒相比,通常饮酒可降低风险(比值比=0.57,95%CI:0.37-0.86)。轻度饮酒对溃疡性结肠炎的发生有保护作用。但当包括吸烟因素时,这种反比关系就消失了。