Tirali Resmiye E, Bodur Haluk, Sipahi Bilge, Sungurtekin Elif
Department of Pediatric Dentistry, Faculty of Dentistry, University of Baskent, Ankara, Turkey.
Aust Endod J. 2013 Apr;39(1):15-8. doi: 10.1111/j.1747-4477.2010.00266.x. Epub 2010 Oct 24.
The objective of this study was to compare the antimicrobial activity of sodium hypochlorite (NaOCl), chlorhexidine gluconate (CHX) and octenidine hydrochloride (OCT) in different concentrations against endodontic pathogens in vitro. Agar diffusion procedure was used to determine the antimicrobial activity of the tested materials. Enterococcus faecalis, Candida albicans and the mixture of these were used for this study. In the agar diffusion test, 5.25% NaOCl exhibited better antimicrobial effect than the other concentrations of NaOCl for all strains. All concentrations of OCT were effective against C. albicans and E. faecalis. Some 0.2% CHX was ineffective on all microorganisms. Antibacterial effectiveness of all experimental solutions decreased on the mixture of all strains. Decreasing concentrations of NaOCl resulted in significantly reduced antimicrobial effect.
本研究的目的是比较不同浓度的次氯酸钠（NaOCl）、葡萄糖酸氯己定（CHX）和盐酸奥替尼啶（OCT）对根管病原体的体外抗菌活性。采用琼脂扩散法测定受试材料的抗菌活性。粪肠球菌、白色念珠菌及其混合物用于本研究。在琼脂扩散试验中，5.25%的NaOCl对所有菌株的抗菌效果均优于其他浓度的NaOCl。所有浓度的OCT对白色念珠菌和粪肠球菌均有效。约0.2%的CHX对所有微生物均无效。所有实验溶液对所有菌株混合物的抗菌效果均下降。NaOCl浓度降低导致抗菌效果显著降低。
