伤口冲洗液（0.01%次氯酸）与2.5%次氯酸钠对粪肠球菌作用效果的比较
An Comparison of the Effect of Wound Irrigating Solution (0.01% Hypochlorous Acid) and 2.5% Sodium Hypochlorite Against Enterococcus Faecalis.
作者信息
Anwar Saif, Sivalingam Balaji, Vijayakumar Nyklesh, Vivek K, Perumal Lavanya P K, Prabha Esai A
机构信息
Department of Pedodontics and Preventive Dentistry, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India.
Department of Oral and Maxillofacial Surgery, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India.
出版信息
J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S796-S801. doi: 10.4103/jpbs.jpbs_172_22. Epub 2022 Jul 13.
AIM
The aim of this study was to evaluate and compare the antimicrobial activity of normal saline, 2.5% sodium hypochlorite, and 0.01% hypochlorous acid against .
MATERIALS AND METHODS
Antimicrobial activity was assayed by Kirby-Bauer cup-well agar diffusion method. Three cup-wells were bored in each petriplate and were filled with 50 μl of each of the respective test agents. Culture plates were placed in an incubator at 37°C and after 24 hours, the size of the magnification inhibition zone was quantified with a caliper and recorded in respective tables. The experiment was reiterated ten times for each reagent, and the diameter of the magnification inhibition zones caused by the irrigation solutions was recorded. The antimicrobial activity of the three test solutions was determined.
RESULTS
The antibacterial property of the three groups was compared by utilizing ANOVA test. The association was found to be statistically significant ( = 0.000). The antibacterial property between 2.5% NaOCl and 0.01% HOCl was further compared with independent test. This association was however not statistically significant ( = 0.02).
目的
本研究旨在评估和比较生理盐水、2.5%次氯酸钠和0.01%次氯酸对……的抗菌活性。
材料与方法
采用 Kirby-Bauer 杯碟琼脂扩散法测定抗菌活性。在每个培养皿中钻三个杯孔，分别加入50μl各自的测试剂。将培养皿置于37°C培养箱中，24小时后，用卡尺测量抑菌圈大小并记录在相应表格中。每种试剂重复实验十次，记录冲洗液引起的抑菌圈直径。测定三种测试溶液的抗菌活性。
结果
采用方差分析比较三组的抗菌性能。发现该关联具有统计学意义（=0.000）。进一步用独立检验比较2.5% NaOCl和0.01% HOCl之间的抗菌性能。然而，这种关联没有统计学意义（=0.02）。
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