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肌肉蛋白质合成的合成代谢抵抗与衰老。

Anabolic resistance of muscle protein synthesis with aging.

机构信息

Department of Human Movement Sciences, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.

出版信息

Exerc Sport Sci Rev. 2013 Jul;41(3):169-73. doi: 10.1097/JES.0b013e318292f3d5.

DOI:10.1097/JES.0b013e318292f3d5
PMID:23558692
Abstract

Aging has been associated with a reduced muscle protein synthetic response to protein intake, termed "anabolic resistance." Physical activity performed before protein intake increases the use of protein-derived amino acids for postprandial muscle protein accretion in senescent muscle. Thus, the level of habitual physical activity may be fundamental to maintain the anabolic responsiveness to protein intake with aging.

摘要

衰老是与肌肉蛋白对蛋白质摄入的合成反应减少有关,这被称为“合成代谢抵抗”。在摄入蛋白质之前进行的体力活动会增加蛋白质衍生氨基酸在衰老肌肉中的餐后肌肉蛋白合成。因此,习惯性体力活动的水平可能是维持蛋白质摄入与衰老时的合成代谢反应能力的基础。

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