芥菜（种子）对链脲佐菌素诱导的糖尿病雄性白化大鼠的降血糖作用。
Hypoglycemic effect of Brassica juncea (seeds) on streptozotocin induced diabetic male albino rat.
作者信息
Thirumalai T, Therasa S Viviyan, Elumalai E K, David E
机构信息
P.G. and Research Department of Zoology, Voorhees College, Physiology wing, Vellore-632 001(T.N.), India.
出版信息
Asian Pac J Trop Biomed. 2011 Aug;1(4):323-5. doi: 10.1016/S2221-1691(11)60052-X.
Abstract
OBJECTIVE
To evaluate the hypoglycemic effect of Brassica juncea (seeds) on streptozotocin induced diabetic male albino rats.
METHODS
Hypoglycemic activity of Brassica juncea (seeds) aqueous extract at a dose of 250, 350 and 450 mg/kg body weight was evaluated. Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated.
RESULTS
The serum insulin levels were recorded a significant depletion in all groups, short term as well as long term diabetic animals, when compared to that of normal animals. A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term groups.
CONCLUSIONS
The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat.
摘要
目的
评估芥菜（种子）对链脲佐菌素诱导的糖尿病雄性白化大鼠的降血糖作用。
方法
评估了剂量为250、350和450毫克/千克体重的芥菜（种子）水提取物的降血糖活性。每组选用6只成年雄性瑞士白化大鼠进行研究和评估。
结果
与正常动物相比，所有组（短期和长期糖尿病动物）的血清胰岛素水平均显著降低。在短期和长期组中，种子提取物对血清胰岛素均有显著的剂量依赖性增强作用。
结论
芥菜种子水提取物对雄性白化大鼠具有显著的降血糖活性。
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