Muthaiah Vijaya Prakash Krishnan, Nathan Abel Arul, Balakrishnan Anandan, Rose Rajiv, Gopalsamy Jayaraman
Frontier Mediville (Special Economic Zone), A Unit of Cherian Heart Foundation, Chennai, India.
Indian J Occup Environ Med. 2012 May;16(2):84-7. doi: 10.4103/0019-5278.107084.
The association between spray paint exposure and bone remodeling received little attention despite the high usage of spray paints in automobile industries, steel furniture workshops etc.
The present study was aimed at investigating the level of serum markers of bone formation in spray painters. The spray painting subjects were selected from automobile body repair workshops in Chennai region of TamilNadu which constitutes 30% of India's automobile industry.
All the study subjects, exposed to spray paint were working in a workshop without standard spraying room and did not wore any aerosol removing respirator. The controls were selected from random population irrespective of occupation. Data relevant to the socioeconomic features and personal history was collected using a questionnaire. The current study included 50 spray painters and 25 control subjects of same age group.
We examined the level of serum calcium, serum phosphorus, serum differentiation markers of bone such as alkaline phosphatase (bone specific) and serum osteocalcin in which these levels were found to be high in serum of spray painters.
The current study concludes dysregulation in bone remodeling of spray painters exposed to chronic solvents and paint pigments.
尽管喷漆在汽车工业、钢制家具车间等行业中使用广泛，但喷漆暴露与骨重塑之间的关联却很少受到关注。
本研究旨在调查喷漆工人血清中骨形成标志物的水平。喷漆受试者选自泰米尔纳德邦钦奈地区的汽车车身修理车间，该地区占印度汽车工业的30%。
所有接触喷漆的研究对象均在没有标准喷漆室的车间工作，且未佩戴任何去除气雾剂的呼吸器。对照组从随机人群中选取，不考虑职业。使用问卷收集与社会经济特征和个人病史相关的数据。本研究包括50名喷漆工人和25名同年龄组的对照对象。
我们检测了血清钙、血清磷、骨分化标志物如碱性磷酸酶（骨特异性）和血清骨钙素的水平，发现喷漆工人血清中这些水平较高。
本研究得出结论，长期接触溶剂和油漆颜料的喷漆工人骨重塑失调。
