Scherer W F, Anderson K
Am J Epidemiol. 1975 Apr;101(4):356-61. doi: 10.1093/oxfordjournals.aje.a112104.
Nine strains of Venezuelan encephalitis (VE) virus isolated from the Amazon region of Peru in 1971 were identified as antigenic subtype I based on plaque-reduction neutralization tests with four and 20 units of antibody. A tenth strain, 71D1252, was possibly a new subtype, but was related to subtypes I and III. Hemagglutinins of each strain made from infected mouse brains had optimals pHs of 6.2 and 6.4. Nine strains were pathogenic for adult hamsters and adult mice, but strain 71D1252 inapparently infected some adult hamsters and mice inoculated peripherally. Plaques of nine strains in Vero African green monkey kidney cell cultures were intermediate in size between representative epizootic and enzootic strains, but plaques of strain 71D1252 were small like epizootic strains.
1971年从秘鲁亚马逊地区分离出的9株委内瑞拉脑炎（VE）病毒，基于用4个单位和20个单位抗体进行的蚀斑减少中和试验，被鉴定为抗原亚型I。第10株病毒71D1252可能是一个新亚型，但与亚型I和III相关。由感染小鼠脑制备的各株病毒血凝素的最适pH值为6.2和6.4。9株病毒对成年仓鼠和成年小鼠具有致病性，但71D1252株病毒对外周接种的一些成年仓鼠和小鼠呈隐性感染。9株病毒在非洲绿猴肾细胞（Vero）培养物中的蚀斑大小介于代表性流行株和地方流行株之间，但71D1252株病毒的蚀斑较小，类似流行株。
