Scherer W F, Chin J
Am J Trop Med Hyg. 1983 Jul;32(4):871-6. doi: 10.4269/ajtmh.1983.32.871.
In 1971, an unusual strain of Venezuelan encephalitis (VE) virus (71D1252) was recovered from the same small area of a rain forest in the western Amazon basin of South America near Iquitos, Loreto, Peru, from which strains of subtype I-D were recovered. The marker characteristics of this strain resembled most closely those of VE subtype III (Mucambo) and were distinctly different from coexisting I-D strains. Thus the concurrent presence of two different VE virus subtypes in one place was a striking exception to the usual geographic allopatry of VE virus subtypes. Strain 71D1252 also contained temperature sensitive (ts) (37 degrees C versus 39 degrees C) virions in the original mosquito suspension and first suckling mouse passage brain tissue suspensions. It thus represents one of the few so-far-reported ts strains of viruses found in nature, and the only natural ts strain of VE virus.
1971年，在秘鲁洛雷托伊基托斯附近的南美洲亚马逊盆地西部雨林的同一小区域内，分离出一种不寻常的委内瑞拉脑炎（VE）病毒株（71D1252），该区域也曾分离出I-D亚型毒株。该毒株的标记特征与VE III型（穆坎博）最为相似，与共存的I-D毒株明显不同。因此，在一个地方同时存在两种不同的VE病毒亚型，这是VE病毒亚型通常的地理异域分布的一个显著例外。71D1252毒株在原始蚊虫悬液以及首次乳鼠传代脑组织悬液中还含有温度敏感（ts）（37℃与39℃）病毒粒子。因此，它是自然界中迄今为止报道的少数ts病毒株之一，也是VE病毒唯一的天然ts毒株。
