Centers for Disease Control and Prevention/National Center for Health Statistics, Division of National Health and Nutrition Examination Surveys, Hyattsville, MD, USA.
J Nutr. 2013 Jun;143(6):872-7. doi: 10.3945/jn.112.169326. Epub 2013 Apr 24.
During pregnancy, the iodine requirement rises to meet demands for neurological development and fetal growth. If these requirements are not met, irreversible pathological cognitive and behavioral changes to the fetus may ensue. This study estimated the prevalence of iodine-containing dietary supplement (DS) use and intakes of iodine from DSs among pregnant women and nonpregnant women of reproductive age (15-39 y) who were interviewed and examined in NHANES 1999-2006 (n = 6404). Although 77.5% of pregnant women reported taking one or more DSs in the past 30 d, only 22.3% consumed an iodine-containing supplement. Most pregnant women reported using one DS and reported taking this product daily. The vast majority of iodine-containing DSs reported by pregnant women claimed an iodine content of 150 μg iodine/serving on the label. Pregnant women using at least one DS containing iodine had a mean daily iodine intake of 122 μg/d from supplements; the median value was 144 μg/d. Median urinary iodine concentrations (UICs) were similar for pregnant and nonpregnant women in the population aged 15-39 y. The median UIC was 148 μg/L for pregnant women and 133 μg/L for nonpregnant women. The WHO has established a cutoff for insufficient iodine intake at <150 μg/L for pregnant women and <100 mg/L for those who are not pregnant. This suggests that as a population, we may not be meeting adequate intakes of iodine for pregnant women. More research is needed on the iodine intakes of pregnant women and women of reproductive age on their total iodine intake from all sources, not just DSs.
在怀孕期间,碘的需求量会增加,以满足胎儿神经发育和生长的需求。如果这些需求得不到满足,可能会对胎儿造成不可逆转的病理性认知和行为改变。本研究通过对 1999-2006 年进行的 NHANES 调查(n=6404)中接受访谈和检查的孕妇和育龄期(15-39 岁)非孕妇的碘摄入情况进行估计,发现孕妇中含碘膳食补充剂(DS)的使用情况和碘摄入量的情况。尽管 77.5%的孕妇在过去 30 天内报告服用了一种或多种 DS,但只有 22.3%的孕妇服用了含碘补充剂。大多数孕妇报告使用一种 DS,并且每天都服用这种产品。孕妇报告的绝大多数含碘 DS 声称标签上的碘含量为 150μg 碘/份。至少服用一种含碘 DS 的孕妇从补充剂中获得的平均每日碘摄入量为 122μg/d;中位数为 144μg/d。在 15-39 岁的人群中,孕妇和非孕妇的尿碘浓度(UIC)中位数相似。孕妇的 UIC 中位数为 148μg/L,非孕妇的 UIC 中位数为 133μg/L。世界卫生组织(WHO)将孕妇碘摄入不足的标准定为<150μg/L,非孕妇的标准定为<100μg/L。这表明,作为一个群体,我们可能无法满足孕妇的碘摄入需求。需要对孕妇和育龄期妇女的碘摄入量进行更多研究,了解其从所有来源(不仅仅是 DS)中摄入的总碘量。