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分析复发预防因素及其对治疗完成后持续戒断的预测能力。

An analysis of relapse prevention factors and their ability to predict sustained abstinence following treatment completion.

机构信息

Integrated Substance Abuse Programs, Department of Psychiatry & Biobehavioral Sciences, University of California-Los Angeles, CA 90025, USA.

出版信息

Am J Addict. 2013 May-Jun;22(3):206-11. doi: 10.1111/j.1521-0391.2012.00328.x.

Abstract

BACKGROUND & OBJECTIVES: This study assessed the role of 14 specific relapse-prevention activities and their underlying factors in maintaining abstinence among subjects (N = 302) completing outpatient treatment for stimulant dependence.

METHODS

We examined what broader dimensions might subsume the 14 items constituting the Drug Avoidance Activities checklist (Farabee et al. J Subst Abuse Treat 2002;23:343-350), and how well these derived factors predicted concurrent drug use at baseline and again 3 and 12 months later.

RESULTS

Although four factors were identified consistently for the three time points, only avoidance strategies had sufficient internal consistency to be retained for further analysis. Controlling for age, gender, and ethnicity, the avoidance subscale was a significant predictor of UA results at all time periods: a one-point increase in the avoidance strategies scale was associated with an 86% increase in odds of a negative UA at baseline (OR = 1.86, 95% CI = 1.37-2.53, p < .001), a 77% increase at 3-month follow-up (OR = 1.77, CI = 1.37-2.29, p < .001), and a 37% increase at 12-month follow-up (OR = 1.37, CI = 1.04-1.81, p = .026).

CONCLUSIONS

Although correlations of individual items with UA results showed statistically significant (p < .05) results for 8 of 14 items at one or more observation points, avoidance-related behaviors showed the strongest associations with sustained abstinence.

摘要

背景与目的

本研究评估了 14 项特定的预防复发活动及其在维持接受门诊治疗的兴奋剂依赖者(N=302)戒断方面的潜在因素的作用。

方法

我们研究了构成药物回避活动清单(Farabee 等人,J Subst Abuse Treat 2002;23:343-350)的 14 项内容可能归入的更广泛维度,以及这些派生因素在基线以及 3 个月和 12 个月后对同期药物使用的预测程度。

结果

尽管在三个时间点都确定了四个因素,但只有回避策略具有足够的内部一致性,可进一步进行分析。控制年龄、性别和种族后,回避子量表是所有时间段尿液分析结果的显著预测因素:回避策略量表的一分增加与基线时尿液分析呈阴性的几率增加 86%相关(OR=1.86,95%CI=1.37-2.53,p<.001),在 3 个月随访时增加 77%(OR=1.77,CI=1.37-2.29,p<.001),在 12 个月随访时增加 37%(OR=1.37,CI=1.04-1.81,p=0.026)。

结论

虽然单个项目与尿液分析结果的相关性显示,在一个或多个观察点,14 个项目中的 8 个项目的相关性具有统计学意义(p<.05),但回避相关行为与持续戒断的关联最强。

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本文引用的文献

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Adoption of drug avoidance activities among patients in contingency management and cognitive-behavioral treatments.
J Subst Abuse Treat. 2002 Dec;23(4):343-50. doi: 10.1016/s0740-5472(02)00297-0.
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Relapse prevention: introduction and overview of the model.预防复发:模型介绍与概述
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