Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY, USA.
Prog Cardiovasc Dis. 2013 May-Jun;55(6):582-9. doi: 10.1016/j.pcad.2013.03.001. Epub 2013 Apr 6.
The connection between the heart and the brain has long been anecdotally recognized but has systematically been studied only relatively recently. Cardiac arrhythmias, especially ventricular arrhythmias that can lead to sudden cardiac death, remain a major public health concern and there is mounting evidence that psychological distress plays a critical role both as a predictor of high-risk cardiac substrate and as an inciting trigger. The transient, unpredictable nature of emotions and cardiac arrhythmias has made their study challenging, but evolving technologies in monitoring and imaging along with larger epidemiological data sets have encouraged more sophisticated studies examining this relationship. Here we review the research on psychological distress including anger, depression and anxiety on cardiac arrhythmias, insights into proposed mechanisms, and potential avenues for future research.
心脏和大脑之间的联系早已被人们津津乐道，但直到最近才被系统地研究。心律失常，尤其是可能导致心源性猝死的室性心律失常，仍然是一个主要的公共卫生关注点，越来越多的证据表明，心理困扰既是高危心脏基质的预测因素，也是诱发因素。情绪和心律失常的短暂性、不可预测性使得它们的研究具有挑战性，但监测和成像技术的不断发展以及更大的流行病学数据集鼓励了更复杂的研究来检验这种关系。在这里，我们回顾了关于心理困扰（包括愤怒、抑郁和焦虑）对心律失常的研究，探讨了其潜在机制和未来研究的方向。
