Houtchens Maria
Brigham and Women's Hospital, Harvard Medical School, Brookline, Massachusetts, USA.
Clin Obstet Gynecol. 2013 Jun;56(2):342-9. doi: 10.1097/GRF.0b013e31828f272b.
Multiple sclerosis (MS) is a chronic neurological illness affecting adults at the time when they are most likely to consider starting a family. It is known that the risk of MS relapse declines during pregnancy but increases in the first 3 to 6 months postpartum. It is also known that this risk is not affected by delivery method, anesthesia type, or parity. Unanswered questions remain, including long-term pregnancy effects on MS outcomes, effects of lactation on postpartum relapses, or the best management strategies of MS patients through reproductive cycle. This review provides information and guidelines for counseling patients with MS desiring motherhood.
多发性硬化症(MS)是一种慢性神经疾病,常在成年人最有可能考虑生育时发病。已知MS复发风险在孕期会降低,但在产后最初3至6个月会增加。还已知这种风险不受分娩方式、麻醉类型或产次影响。仍有一些问题未得到解答,包括妊娠对MS病情转归的长期影响、哺乳对产后复发的影响,以及MS患者在整个生殖周期的最佳管理策略。本综述为向有生育意愿的MS患者提供咨询提供信息和指导方针。