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脱钙异体骨基质与口腔内游离骨自体移植治疗牙周骨内缺损的疗效比较

The comparative efficacy of decalcified allogenic bone matrix and intra-oral free osseous autografts in the treatment of periodontal intrabony defects.

作者信息

Jindal Vikas, Gill Amarjit Singh, Kapoor Daljit, Gupta Harinder

机构信息

Department of Periodontics, Himachal Dental College, Sundernagar, Mandi, Himachal Pradesh, India.

出版信息

J Indian Soc Periodontol. 2013 Jan;17(1):91-5. doi: 10.4103/0972-124X.107482.

DOI:10.4103/0972-124X.107482
PMID:23633781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3636953/
Abstract

BACKGROUND AND OBJECTIVES

The primary goal of periodontal treatment is the maintenance of the natural dentition in health and comfortable function. The shift in therapeutic concepts from resection to regeneration has significantly impacted the practice of periodontology. The objective of the present study is to compare the relative efficacy of intra-oral autogenous graft and decalcified allogenic bone matrix (DABM) in the treatment of periodontal intrabony defects.

MATERIALS AND METHODS

In the present study, 30 patients in the age group of 30-50 years with two almost identical intrabony defects, on either side of the mouth/upper and lower jaw, based upon the radiographic observations were selected from amongst the patients visiting the Department of Periodontology and Oral Medicine, Punjab Government Dental College and Hospital, Amritsar. One of the defect was selected randomly and filled with autogenous cancellous graft and the other with DABM. Post-operative assessment was done by taking radiographs, 12 weeks and 24 weeks post-operatively.

RESULTS

Definite bone fill was achieved both with intra-oral free osseous autograft and with DABM at 12 weeks observation, which further increased significantly at 24 weeks observation. The bone fill obtained with intra-oral free osseous autograft was found to be significantly higher than that with DABM both at 12 weeks and 24 weeks post-operative observation.

CONCLUSION

Within the limitations of this study, it establishes the superiority of the intra-oral free osseous autograft over that of DABM graft in correcting the intrabony defects.

摘要

背景与目的

牙周治疗的主要目标是维持天然牙列的健康和舒适功能。治疗理念从切除向再生的转变对牙周病学的实践产生了重大影响。本研究的目的是比较口腔内自体骨移植和脱钙异体骨基质(DABM)在治疗牙周骨内缺损中的相对疗效。

材料与方法

在本研究中,从阿姆利则旁遮普政府牙科学院和医院牙周病与口腔医学科就诊的患者中,根据影像学观察,选取30名年龄在30至50岁之间、口腔两侧/上下颌有两个几乎相同骨内缺损的患者。随机选择其中一个缺损,用自体松质骨移植填充,另一个用DABM填充。术后分别在12周和24周时通过拍摄X光片进行评估。

结果

在12周观察时,口腔内游离骨自体移植和DABM均实现了明确的骨填充,在24周观察时进一步显著增加。在术后12周和24周观察时,发现口腔内游离骨自体移植获得的骨填充明显高于DABM。

结论

在本研究的局限性范围内,证实了口腔内游离骨自体移植在纠正骨内缺损方面优于DABM移植。

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