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姜黄素在全身健康和口腔健康中的作用:综述。

Role of curcumin in systemic and oral health: An overview.

作者信息

Nagpal Monika, Sood Shaveta

机构信息

Department of Oral Pathology, Dr. H.S. Judge Institute of Dental Sciences and Hospital, Punjab University, Chandigarh, India.

出版信息

J Nat Sci Biol Med. 2013 Jan;4(1):3-7. doi: 10.4103/0976-9668.107253.

DOI:10.4103/0976-9668.107253
PMID:23633828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3633300/
Abstract

Various modalities of treatment are available for different dental diseases, but the major drawback of these conventional drug therapies is the numerous side effects associated with their use. This has led to renewed interest in the discovery of novel anti-infective natural compounds derived from plants. Plants have been the major source of medicine since the time immemorial. Turmeric has been attributed a number of medicinal properties in the traditional system of medicine. The objective of this article is to review the efficacy of turmeric herb in maintenance of oral health, in particular, and overall health, in general. Turmeric, a rhizome of Curcuma longa, is a herb known for its medicinal properties and is a more acceptable and viable option for a common man. It has proven properties like anti-inflammatory, antioxidant, antimicrobial, hepatoprotective, immunostimulant, antiseptic, and antimutagenic. Due to these properties, it is quite useful in dentistry as well. It has a role in the treatment of periodontal diseases and oral cancers. Turmeric can also be used as a pit and fissure sealant, mouth wash, and subgingival irrigant in different preparations. It can also be used as a component in local drug delivery system in gel form.

摘要

针对不同的牙科疾病有多种治疗方式,但这些传统药物疗法的主要缺点是使用时会产生诸多副作用。这使得人们重新对从植物中发现新型抗感染天然化合物产生兴趣。自古以来,植物一直是药物的主要来源。在传统医学体系中,姜黄具有多种药用特性。本文的目的是综述姜黄在维持口腔健康尤其是整体健康方面的功效。姜黄是姜科植物姜黄的根茎,是一种以其药用特性而闻名的草药,对普通人来说是更可接受且可行的选择。它具有抗炎、抗氧化、抗菌、保肝、免疫刺激、防腐和抗诱变等已被证实的特性。由于这些特性,它在牙科领域也非常有用。它在治疗牙周疾病和口腔癌方面发挥作用。姜黄还可以制成不同制剂用作窝沟封闭剂、漱口水和龈下冲洗剂。它也可以作为凝胶形式的局部给药系统的一种成分。

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本文引用的文献

1
Comparative evaluation of turmeric and chlorhexidine gluconate mouthwash in prevention of plaque formation and gingivitis: a clinical and microbiological study.姜黄与葡萄糖酸氯己定漱口水预防牙菌斑形成和牙龈炎的比较评价:一项临床和微生物学研究。
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Evaluation of local drug-delivery system containing 2% whole turmeric gel used as an adjunct to scaling and root planing in chronic periodontitis: A clinical and microbiological study.含2%全姜黄凝胶的局部给药系统作为慢性牙周炎龈下刮治和根面平整辅助治疗的评估:一项临床和微生物学研究。
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Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma.姜黄素:对头颈部鳞状细胞癌的抗癌特性和治疗活性的综述。
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4
Uses of turmeric in dentistry: an update.姜黄在牙科中的应用:最新进展。
Indian J Dent Res. 2009 Jan-Mar;20(1):107-9. doi: 10.4103/0970-9290.49065.
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Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy.聚合物纳米颗粒包裹的姜黄素(“纳米姜黄素”):一种人类癌症治疗的新策略。
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Phase II clinical trial on effect of the long turmeric (Curcuma longa Linn) on healing of peptic ulcer.姜黄(Curcuma longa Linn)对消化性溃疡愈合作用的II期临床试验。
Southeast Asian J Trop Med Public Health. 2001 Mar;32(1):208-15.
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Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo.姜黄素在人类前列腺癌中的治疗潜力。III. 姜黄素在体内抑制LNCaP前列腺癌细胞的增殖、诱导其凋亡并抑制血管生成。
Prostate. 2001 Jun 1;47(4):293-303. doi: 10.1002/pros.1074.
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Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress.姜黄素是一种抗氧化剂和抗炎剂,可诱导血红素加氧酶-1的产生,并保护内皮细胞免受氧化应激的影响。
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A simple and efficient separation of the curcumins, the antiprotozoal constituents of Curcuma longa.姜黄中抗原生动物成分姜黄素的一种简单高效分离方法。
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