Division of Gastroenterology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Gastroenterol Clin North Am. 2013 Jun;42(2):211-7. doi: 10.1016/j.gtc.2013.01.002. Epub 2013 Feb 21.
This review provides a state of the art description of gastric cancer etiology, the infectious agent, host factors, the precancerous cascade, clinical aspects, and prevention strategies. The biology of Helicobacter pylori, the primary causative agent, is discussed as well as the environmental factors that may modulate its effects.
本文综述了胃癌的病因学、病原体、宿主因素、癌前级联反应、临床方面和预防策略的最新进展。本文还讨论了主要病原体幽门螺杆菌的生物学特性,以及可能调节其作用的环境因素。