Sleep Medicine Centre Kempenhaeghe, Heeze, The Netherlands.
Sleep Med. 2013 Jul;14(7):668-74. doi: 10.1016/j.sleep.2013.03.010. Epub 2013 May 3.
Impaired bed mobility (IBM) may be an important reason for the high prevalence of sleep insomnia in Parkinson disease (PD). Here we assessed the influence of subjectively IBM on both subjective and objective sleep parameters in insomnia PD patients with (PD+IBM) and without (PD-IBM) concerns of IBM and controls with primary insomnia.
We included 44 PD patients with sleep initiation or maintenance concerns and 44 control subjects with primary insomnia. Sleep questionnaires, polysomnographic sleep parameters, activity data, and the number of body position changes were compared between PD patients and controls as well as within the PD group between PD+IBM vs PD-IBM subjects.
There were 54.5% of PD subjects who reported having IBM. In the PD+IBM group, the number of body position changes was significantly lower than in PD-IBM (0.4/h [0.0-1.8] vs 1.4/h [0.0-4.6], P=.015). Sleep efficiency (SE) was lower in PD+IBM patients (63.5; 26.2-85.6) compared to PD-IBM patients (78.4; 54.8-92.6; P<.001).
PD patients who report IBM have fewer sleep-related body position changes (i.e., nocturnal hypokinesia) than PD patients without such concerns. Furthermore, objective SE is significantly diminished in these patients.
行动不便（IBM）可能是帕金森病（PD）患者睡眠失眠高发的一个重要原因。在这里，我们评估了主观 IBM 对伴有（PD+IBM）和不伴（PD-IBM）IBM 担忧的失眠 PD 患者以及原发性失眠对照者的主观和客观睡眠参数的影响。
我们纳入了 44 名有睡眠起始或维持问题的 PD 患者和 44 名原发性失眠对照者。比较 PD 患者和对照组之间以及 PD 组内 PD+IBM 与 PD-IBM 患者之间的睡眠问卷、多导睡眠图睡眠参数、活动数据和体位变化次数。
有 54.5%的 PD 患者报告有 IBM。在 PD+IBM 组中，体位变化次数明显低于 PD-IBM 组（0.4/h[0.0-1.8]vs 1.4/h[0.0-4.6]，P=.015）。PD+IBM 患者的睡眠效率（SE）较低（63.5；26.2-85.6），与 PD-IBM 患者（78.4；54.8-92.6；P<.001）相比。
报告 IBM 的 PD 患者比不伴有此类担忧的 PD 患者睡眠相关体位变化（即夜间运动减少）更少。此外，这些患者的客观 SE 显著降低。
