Kloskowski Tomasz, Kowalczyk Tomasz, Nowacki Maciej, Drewa Tomasz
Tissue Engineering Department, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Int J Artif Organs. 2013 Jun 25;36(6):392-405. doi: 10.5301/ijao.5000130. Epub 2013 May 6.
Large ureter damages are difficult to reconstruct. Current techniques are complicated, difficult to perform, and often associated with failures. The ureter has never been regenerated thus far. Therefore the use of tissue engineering techniques for ureter reconstruction and regeneration seems to be a promising way to resolve these problems. For proper ureter regeneration the following problems must be considered: the physiological aspects of the tissue, the type and shape of the scaffold, the type of cells, and the specific environment (urine). This review presents tissue engineering achievements in the field of ureter regeneration focusing on the scaffold, the cells, and ureter healing.
大型输尿管损伤难以修复。目前的技术复杂，操作困难，且常常伴随着失败。迄今为止，输尿管从未实现过再生。因此，利用组织工程技术进行输尿管修复和再生似乎是解决这些问题的一种很有前景的方法。为了实现输尿管的正常再生，必须考虑以下问题：组织的生理特性、支架的类型和形状、细胞的类型以及特定环境（尿液）。本文综述了输尿管再生领域的组织工程成果，重点关注支架、细胞和输尿管愈合。
