1Department of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Angiology. 2014 Feb;65(2):147-51. doi: 10.1177/0003319713488932. Epub 2013 May 8.
We investigated the association between coronary artery ectasia (CAE) and Neutrophil-to-lymphocyte ratio (NLR), an indicator of the inflammatory state. The study population included 434 patients (247 males, mean age 62 ± 10 years) including 230 patients with isolated CAE and 104 patients with coronary artery disease and 100 patientss with normal coronary arteries. The NLR was measured at admission and 30 days after coronary angiography in all the patients. The NLR was significantly higher in patients with CAE than those with normal coronary arteries (2.2 ± 0.6-1.3 ± 0.6, P < .001). Linear regression analyses revealed that NLR (coefficient β = -.61, P < .001) was significantly associated with severity of CAE. The NLR is significantly higher in patients with CAE compared to controls with normal coronary arteries, and NLR is associated with severity of CAE.
我们研究了冠状动脉扩张（CAE）与中性粒细胞与淋巴细胞比值（NLR）之间的关联，NLR 是炎症状态的一个指标。研究人群包括 434 名患者（247 名男性，平均年龄 62 ± 10 岁），其中 230 名患者为单纯 CAE，104 名患者为冠心病，100 名患者为正常冠状动脉。所有患者在冠状动脉造影入院时和 30 天后测量 NLR。CAE 患者的 NLR 明显高于正常冠状动脉患者（2.2 ± 0.6-1.3 ± 0.6，P <.001）。线性回归分析显示，NLR（系数β=-.61，P <.001）与 CAE 的严重程度显著相关。与正常冠状动脉的对照组相比，CAE 患者的 NLR 明显更高，并且 NLR 与 CAE 的严重程度相关。
