DNA复制：驶过四链障碍 - Suppr | 超能文献

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DNA replication: driving past four-stranded snags.DNA复制：驶过四链障碍

Nature. 2013 May 23;497(7450):449-50. doi: 10.1038/nature12244. Epub 2013 May 8.

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Pif1 family helicases suppress genome instability at G-quadruplex motifs.Pif1 家族解旋酶抑制 G-四链体基序处的基因组不稳定性。

Nature. 2013 May 23;497(7450):458-62. doi: 10.1038/nature12149. Epub 2013 May 8.

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Complementary roles of Pif1 helicase and single stranded DNA binding proteins in stimulating DNA replication through G-quadruplexes.Pif1 解旋酶和单链 DNA 结合蛋白在通过 G-四链体刺激 DNA 复制中的互补作用。

Nucleic Acids Res. 2019 Sep 19;47(16):8595-8605. doi: 10.1093/nar/gkz608.

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DNA-unwinding activity of Pif1 is modulated by thermal stability, folding conformation, and loop lengths of G-quadruplex DNA.Pif1 的 DNA 解旋活性受热稳定性、折叠构象和 G-四链体 DNA 环长度的调节。

J Biol Chem. 2018 Nov 30;293(48):18504-18513. doi: 10.1074/jbc.RA118.005071. Epub 2018 Oct 10.

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Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability.Mms1在酿酒酵母中与富含G的区域结合，并影响复制和基因组稳定性。

Nucleic Acids Res. 2017 Jul 27;45(13):7796-7806. doi: 10.1093/nar/gkx467.

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[G4-quadruplexes and genome instability].[G4四链体与基因组不稳定性]

Mol Biol (Mosk). 2013 Mar-Apr;47(2):224-31. doi: 10.7868/s0026898413020183.

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DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase.酵母 Pif1 DNA 解旋酶促进 G-四链体基序的 DNA 复制。

Cell. 2011 May 27;145(5):678-91. doi: 10.1016/j.cell.2011.04.015.

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Yeast Genome Maintenance by the Multifunctional PIF1 DNA Helicase Family.多功能PIF1 DNA解旋酶家族对酵母基因组的维持作用

Genes (Basel). 2020 Feb 20;11(2):224. doi: 10.3390/genes11020224.

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Mgs1 protein supports genome stability via recognition of G-quadruplex DNA structures.Mgs1 蛋白通过识别 G-四链体 DNA 结构来支持基因组稳定性。

FASEB J. 2020 Sep;34(9):12646-12662. doi: 10.1096/fj.202000886R. Epub 2020 Aug 4.

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Molecular mechanism of G-quadruplex unwinding helicase: sequential and repetitive unfolding of G-quadruplex by Pif1 helicase.G-四链体解旋酶的分子机制：Pif1解旋酶对G-四链体的顺序性和重复性解折叠

Biochem J. 2015 Feb 15;466(1):189-99. doi: 10.1042/BJ20140997.

引用本文的文献

1

Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation.人类基因组中富含G4形成重复序列与稳健且协调良好的转录以及癌症转录组变异减少有关。

J Biol Chem. 2024 Nov;300(11):107822. doi: 10.1016/j.jbc.2024.107822. Epub 2024 Sep 26.

2

Up-regulated PIF1 predicts poor clinical outcomes and correlates with low immune infiltrates in clear cell renal cell carcinoma.上调的PIF1预示着透明细胞肾细胞癌患者的临床预后较差，且与低免疫浸润相关。

Front Genet. 2023 Jan 4;13:1058040. doi: 10.3389/fgene.2022.1058040. eCollection 2022.

3

The biofilm matrix scaffold of Pseudomonas aeruginosa contains G-quadruplex extracellular DNA structures.

本文引用的文献

1

Pif1 family helicases suppress genome instability at G-quadruplex motifs.Pif1 家族解旋酶抑制 G-四链体基序处的基因组不稳定性。

Nature. 2013 May 23;497(7450):458-62. doi: 10.1038/nature12149. Epub 2013 May 8.

2

The G4 genome.G4基因组。

PLoS Genet. 2013 Apr;9(4):e1003468. doi: 10.1371/journal.pgen.1003468. Epub 2013 Apr 18.

3

Quantitative visualization of DNA G-quadruplex structures in human cells.定量可视化人细胞中的 DNA G-四链体结构。