Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California-Los Angeles, CA 90048, USA.
Harv Rev Psychiatry. 2013 May-Jun;21(3):138-50. doi: 10.1097/HRP.0b013e3182937116.
To review the literature on quality of life (QoL) in borderline personality disorder (BPD) by examining the use of QoL instruments, the extent of QoL impairments in BPD, and the impact of treatment on QoL in BPD.
Studies were identified through PubMed and PsycINFO searches for articles from 1980 to 2011 using the following keywords: quality of life OR health-related quality of life OR QOL OR HRQOL AND borderline personality disorder. We focused our search on studies that actually measured QoL. Two authors agreed independently on including 25 studies that met specific selection criteria.
The data on QoL in BPD are still sparse, with high heterogeneity in the instruments used to measure QoL, which decreases the comparability of existing studies. EQ-5D, WHOQOL, SF-36, Satisfaction Profile, and Q-LESQ have been utilized as QoL measures in BPD research. The reviewed studies uniformly demonstrated grave impairments in QoL of BPD patients. The available evidence indicates that BPD treatments improve not only psychiatric symptoms but also QoL, as shown by psychotherapy and pharmacotherapy studies. Nevertheless, it remains unclear whether current treatments are able to restore QoL to community norms.
QoL is gaining more importance as an outcome measure of psychiatric interventions. Research evidence confirms that QoL is seriously impaired in BPD and that QoL improves with treatment. Further research is needed to build a consensus on the utilization of QoL measures and to improve their validity in BPD. More importantly, future studies need to develop and test interventions to improve QoL in BPD.
通过考察生活质量（QoL）量表的使用、BPD 患者的生活质量受损程度，以及治疗对 BPD 患者生活质量的影响，来回顾 BPD 患者生活质量的文献。
通过在 PubMed 和 PsycINFO 上检索，使用以下关键词从 1980 年至 2011 年搜索文献：生活质量或健康相关生活质量或 QOL 或 HRQOL 及边缘型人格障碍。我们的搜索重点是实际测量生活质量的研究。两位作者独立地同意纳入 25 项符合特定选择标准的研究。
BPD 患者的生活质量数据仍然很少，用于测量生活质量的工具存在很大的异质性，这降低了现有研究的可比性。EQ-5D、WHOQOL、SF-36、满意度问卷和 Q-LESQ 已被用于 BPD 研究中的生活质量测量。综述的研究一致表明 BPD 患者的生活质量严重受损。现有证据表明，心理治疗和药物治疗研究表明，BPD 治疗不仅能改善精神症状，还能改善生活质量。然而，目前尚不清楚现有的治疗方法是否能将生活质量恢复到社区的正常水平。
生活质量作为精神干预的结果测量指标正变得越来越重要。研究证据证实，BPD 患者的生活质量严重受损，且治疗可改善生活质量。需要进一步的研究来就生活质量测量工具的使用达成共识，并提高其在 BPD 中的有效性。更重要的是，未来的研究需要开发和测试改善 BPD 患者生活质量的干预措施。
