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一种使用 EPR 或荧光技术研究内源性一氧化氮的分子探针设计的新策略。

A new strategy for the design of molecular probes for investigating endogenous nitric oxide using an EPR or fluorescent technique.

机构信息

Department of Applied Chemistry, Faculty of Engineering, Kyushu University, Higashi-ku, Fukuoka, Japan.

出版信息

Chemphyschem. 2001 Nov 19;2(11):655-61. doi: 10.1002/1439-7641(20011119)2:11<655::AID-CPHC655>3.0.CO;2-S.

DOI:10.1002/1439-7641(20011119)2:11<655::AID-CPHC655>3.0.CO;2-S
PMID:23686899
Abstract

A development of a new probe for NO, a molecule of profound biophysiological importance, based on the concept of "spin exchange" is described. This probe, based on the detection of a released TEMPOL radical, offers detection by EPR to 10 nm.

摘要

介绍了一种基于“自旋交换”概念的新型 NO 探针的开发,NO 是一种具有深远生物物理意义的分子。这种探针基于检测释放的 TEMPOL 自由基,可通过 EPR 检测到 10nm。

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