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ORL J Otorhinolaryngol Relat Spec. 2013;75(1):46-53. doi: 10.1159/000347083. Epub 2013 May 9.
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本文引用的文献

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Visualization and analysis of 3D microscopic images.三维微观图像的可视化与分析。
PLoS Comput Biol. 2012;8(6):e1002519. doi: 10.1371/journal.pcbi.1002519. Epub 2012 Jun 14.
2
The Visible Human Projects in Korea and China with improved images and diverse applications.韩国和中国的可视人计划,图像得到改进且应用多样。
Surg Radiol Anat. 2012 Aug;34(6):527-34. doi: 10.1007/s00276-012-0945-8. Epub 2012 Mar 10.
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Virtual temporal bone dissection system: OSU virtual temporal bone system: development and testing.虚拟颞骨解剖系统:OSU 虚拟颞骨系统:开发与测试。
Laryngoscope. 2012 Mar;122 Suppl 1(Suppl 1):S1-12. doi: 10.1002/lary.22499. Epub 2012 Jan 31.
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Training and simulation in otolaryngology.耳鼻喉科的培训与模拟
Otolaryngol Clin North Am. 2011 Dec;44(6):1333-50, viii-ix. doi: 10.1016/j.otc.2011.08.009.
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Teaching Otolaryngology skills through simulation.通过模拟教学耳鼻喉科学技能。
Eur Arch Otorhinolaryngol. 2011 Jul;268(7):949-53. doi: 10.1007/s00405-011-1554-6. Epub 2011 Mar 23.
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Segmentation and surface reconstruction of the detailed ear structures, identified in sectioned images.分段和表面重建详细的耳朵结构,在切片图像中识别。
Anat Rec (Hoboken). 2011 Apr;294(4):559-64. doi: 10.1002/ar.21343. Epub 2011 Mar 1.
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Accuracy of computer-aided geometric 3D reconstruction based on histological serial microgrinding preparation.基于组织学连续微磨片制备的计算机辅助几何三维重建的准确性
Comput Methods Biomech Biomed Engin. 2011 Jul;14(7):581-94. doi: 10.1080/10255842.2010.487049.
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Automatic reconstruction of 3D neuron structures using a graph-augmented deformable model.基于图增强可变形模型的 3D 神经元结构自动重建。
Bioinformatics. 2010 Jun 15;26(12):i38-46. doi: 10.1093/bioinformatics/btq212.
9
Showing their true colors: a practical approach to volume rendering from serial sections.展现真面目:一种从连续切片进行体绘制的实用方法。
BMC Dev Biol. 2010 Apr 21;10:41. doi: 10.1186/1471-213X-10-41.
10
V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets.V3D 能够实时可视化和定量分析大规模生物图像数据集。
Nat Biotechnol. 2010 Apr;28(4):348-53. doi: 10.1038/nbt.1612. Epub 2010 Mar 14.

可免费获取的真彩色容积渲染软件和用于颞骨解剖结构虚拟探索的冷冻组织学数据集。

Freely-available, true-color volume rendering software and cryohistology data sets for virtual exploration of the temporal bone anatomy.

作者信息

Kahrs Lüder Alexander, Labadie Robert Frederick

机构信息

Department of Otolaryngology, Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA. lueder.kahrs @ imes.uni-hannover.de

出版信息

ORL J Otorhinolaryngol Relat Spec. 2013;75(1):46-53. doi: 10.1159/000347083. Epub 2013 May 9.

DOI:10.1159/000347083
PMID:23689270
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4410986/
Abstract

BACKGROUND

Cadaveric dissection of temporal bone anatomy is not always possible or feasible in certain educational environments. Volume rendering using CT and/or MRI helps understanding spatial relationships, but they suffer in nonrealistic depictions especially regarding color of anatomical structures. Freely available, nonstained histological data sets and software which are able to render such data sets in realistic color could overcome this limitation and be a very effective teaching tool.

METHODS

With recent availability of specialized public-domain software, volume rendering of true-color, histological data sets is now possible. We present both feasibility as well as step-by-step instructions to allow processing of publicly available data sets (Visible Female Human and Visible Ear) into easily navigable 3-dimensional models using free software.

RESULTS

Example renderings are shown to demonstrate the utility of these free methods in virtual exploration of the complex anatomy of the temporal bone. After exploring the data sets, the Visible Ear appears more natural than the Visible Human.

CONCLUSION

We provide directions for an easy-to-use, open-source software in conjunction with freely available histological data sets. This work facilitates self-education of spatial relationships of anatomical structures inside the human temporal bone as well as it allows exploration of surgical approaches prior to cadaveric testing and/or clinical implementation.

摘要

背景

在某些教育环境中,颞骨解剖的尸体解剖并不总是可行的。使用CT和/或MRI进行容积再现有助于理解空间关系,但它们在非真实描绘方面存在不足,尤其是在解剖结构的颜色方面。免费可得的、未染色的组织学数据集以及能够以真实颜色再现此类数据集的软件可以克服这一局限性,成为非常有效的教学工具。

方法

随着近期专用公共领域软件的出现,现在可以对真彩色组织学数据集进行容积再现。我们展示了可行性以及逐步说明,以便使用免费软件将公开可用的数据集(可视女性人体和可视耳)处理成易于浏览的三维模型。

结果

示例再现图展示了这些免费方法在虚拟探索颞骨复杂解剖结构中的实用性。在探索数据集后,可视耳看起来比可视人体更自然。

结论

我们提供了结合免费可得的组织学数据集使用易于使用的开源软件的指导。这项工作有助于对人类颞骨内解剖结构的空间关系进行自我教育,并且还允许在尸体测试和/或临床实施之前探索手术方法。