BOLD-fMRI 在阐明偏头痛病理生理学中的作用。
The role of BOLD-fMRI in elucidating migraine pathophysiology.
机构信息
Headache Center, Department of Neurology, Second University of Naples, Naples, Italy.
出版信息
Neurol Sci. 2013 May;34 Suppl 1:S47-50. doi: 10.1007/s10072-013-1383-z.
Migraine is a neurologic disorder characterized by disabling attacks of throbbing headache with specific features and associated symptoms. Despite the recent discoveries in basic neurosciences, migraine pathophysiology is not completely understood. Nevertheless, in the last decades, advances in functional magnetic resonance imaging (fMRI) have significantly provided new insights into migraine mechanisms. Blood oxygen level dependent (BOLD) fMRI technique is the most commonly used method to explore brain function and connectivity due to high temporal and spatial resolution. The purpose of this review is to present a synthesis of recent BOLD-fMRI studies which have allowed us to elucidate the complex process involved in migraine pathophysiology.
偏头痛是一种以搏动性头痛为特征的神经系统疾病，具有特定的特征和相关症状。尽管最近在基础神经科学方面有了新的发现，但偏头痛的病理生理学仍未完全被理解。然而，在过去的几十年里，功能磁共振成像（fMRI）的进步极大地提供了对偏头痛机制的新见解。血氧水平依赖（BOLD）fMRI 技术由于具有较高的时间和空间分辨率，是探索大脑功能和连接的最常用方法。本文综述了最近的 BOLD-fMRI 研究，这些研究使我们能够阐明偏头痛病理生理学中的复杂过程。
Zotero 插件