Adam Stewart I, Paskhover Boris, Sasaki Clarence T
Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, Yale University School of Medicine, Yale Physicians Building, 4th Floor, 800 Howard Ave, New Haven, CT 06510, USA.
Ann Otol Rhinol Laryngol. 2013 Apr;122(4):247-53. doi: 10.1177/000348941312200406.
We used a retrospective chart review to analyze revision endoscopic carbon dioxide (CO2) laser and staple repairs of recurrent Zenker diverticulum (ZD).
The medical records of patients with recurrent ZD after primary endoscopic repair were selected. The chart data included method of repair (CO2 laser or stapler), demographics (age and sex), defect size (in centimeters), preoperative and postoperative symptoms, and complications. Patients' dysphagia was graded on a modified Functional Oral Intake Scale from 1 to 4 (1 being normal intake and 4 being severely limited intake or gastrostomy tube dependence). Regurgitation was also graded on a 1-to-4 scale (1 being no regurgitation and 4 being aspiration).
A total of 148 consecutive patients with ZD were treated with endoscopic repair between 2000 and 2010. Twelve of these patients had revisions after failed primary endoscopic management procedures, all done with the stapler. Eight revision surgeries were performed by CO2 laser, and 4 by stapler repair. No difference was noted in patient age or defect size (laser, 3.06-cm defects; stapler, 2.75-cm defects). The length of hospital stay and the time to oral intake for the patients who had a revision stapler procedure were significantly greater (p values of 0.029 and 0.009) than those for the patients in the primary stapler procedure group. Better postoperative regurgitation scores were noted for patients who had a CO2 laser procedure.
Secondary endoscopic repair for ZD recurrence is an effective treatment method. Better symptom outcomes were observed with secondary CO2 laser repair than with stapler revision. Patients with revision stapling had longer hospital stays and a longer time to oral intake than did patients with primary staple repairs.
我们采用回顾性病历审查的方法,分析复发性Zenker憩室(ZD)的内镜二氧化碳(CO2)激光修复术和吻合器修复术。
选取初次内镜修复术后复发性ZD患者的病历。病历数据包括修复方法(CO2激光或吻合器)、人口统计学信息(年龄和性别)、缺损大小(以厘米为单位)、术前和术后症状以及并发症。患者的吞咽困难程度根据改良的功能性口服摄入量量表从1到4进行分级(1表示正常摄入,4表示严重受限摄入或依赖胃造瘘管)。反流也按1到4级进行分级(1表示无反流,4表示误吸)。
2000年至2010年间,共有148例连续性ZD患者接受了内镜修复治疗。其中12例患者在初次内镜治疗失败后进行了再次修复,均采用吻合器。8例再次手术采用CO2激光,4例采用吻合器修复。患者年龄或缺损大小无差异(激光组缺损3.06厘米;吻合器组缺损2.75厘米)。接受再次吻合器修复手术的患者住院时间和恢复经口进食的时间明显长于初次吻合器手术组患者(p值分别为0.029和0.009)。接受CO2激光手术的患者术后反流评分更好。
ZD复发的二次内镜修复是一种有效的治疗方法。二次CO2激光修复比吻合器修复观察到更好的症状结局。接受再次吻合器修复的患者比初次吻合器修复的患者住院时间更长,恢复经口进食的时间也更长。