Research and Development, BD Biosciences, La Jolla, CA 92037, USA.
Immune Netw. 2013 Apr;13(2):43-54. doi: 10.4110/in.2013.13.2.43. Epub 2013 Apr 30.
Over the past 40 years, flow cytometry has emerged as a leading, application-rich technology that supports high-resolution characterization of individual cells which function in complex cellular networks such as the immune system. This brief overview highlights advances in multiparameter flow cytometric technologies and reagent applications for characterization and functional analysis of cells modulating the immune network. These advances significantly support high-throughput and high-content analyses and enable an integrated understanding of the cellular and molecular interactions that underlie complex biological systems.
在过去的 40 年中，流式细胞术已经成为一种领先的、应用丰富的技术，支持对复杂细胞网络（如免疫系统）中单个细胞的高分辨率特征进行分析。本简要综述重点介绍了用于调节免疫网络的细胞的特征和功能分析的多参数流式细胞术技术和试剂应用的进展。这些进展极大地支持了高通量和高内涵分析，并使人们能够深入了解复杂生物系统中细胞和分子相互作用的基础。
