Nguyen My-Linh T, Lafargue Christopher J, Pua Tarah L, Tedjarati Sean S
Department of Obstetrics and Gynecology, Westchester Medical Center of New York Medical College, Munger Pavilion, Room 617, Valhalla, NY 10595, USA.
Case Rep Obstet Gynecol. 2013;2013:807205. doi: 10.1155/2013/807205. Epub 2013 Apr 22.
Most grade 1 endometrioid endometrial cancers are confined to the uterus at the time of diagnosis and confer a good prognosis. Rarely will a grade 1 endometrioid endometrial carcinoma present with distant metastasis, especially to the bone. We present the case of a 56-year-old woman with postmenopausal bleeding and right hip pain due to metastatic grade 1 endometrioid uterine cancer invading into the right ischium. We discuss treatment options as well as provide a review of prior published reports on bony metastasis in grade 1 endometrioid endometrial cancers. To date, this case is one of 10 others which demonstrates that even a well-differentiated, low-grade endometrioid endometrial carcinoma can progress in a highly aggressive manner.
大多数1级子宫内膜样子宫内膜癌在诊断时局限于子宫，预后良好。1级子宫内膜样子宫内膜癌很少出现远处转移，尤其是骨转移。我们报告了一例56岁绝经后出血且因转移性1级子宫内膜样子宫癌侵犯右侧坐骨而出现右髋部疼痛的女性病例。我们讨论了治疗方案，并对先前发表的关于1级子宫内膜样子宫内膜癌骨转移的报告进行了综述。迄今为止，该病例是另外10例病例之一，这些病例表明，即使是高分化、低级别子宫内膜样子宫内膜癌也可能以高度侵袭性的方式进展。
