Kumar Hemanshi
Department of Endodontics, Sudha Rustagi College of Dental Sciences, N.I.T. Faridabad, Haryana, India.
J Conserv Dent. 2013 Mar;16(2):144-7. doi: 10.4103/0972-0707.108197.
This in vitro study was designed to comparatively evaluate the antimicrobial efficacy of Curcuma longa (turmeric - T1-10%, T2-20%); Tachyspermum ammi (ajwain - A1-10%, A2-20%); chlorhexidine (CHX) gluconate gel (hexigel - 1%); and calcium hydroxide (10%) as intracanal medicaments against Enterococcus faecalis.
Agar plates were prepared using brain-heart infusion (BHI) agar. Cultures of E. faecalis were grown in BHI broth at 37°C. Well diffusion method was used to derive results. Plates were inoculated for 72 h at 37°C and microbial zones of inhibition were recorded. Statistical analysis was performed with repeated measures analysis of variance.
C. longa (T2-20%) and CHX gluconate gel (hexigel - CHX-1%) showed larger zones of microbial inhibition than C. longa (T1-10%) that were statistically significant (P < 0.05) and were highly significant when compared to T. ammi (ajwain - A1 and A2) and calcium hydroxide.
C. longa can be used as intracanal medicament in endodontic failure cases.
本体外研究旨在比较评估姜黄（姜黄 - T1 - 10%，T2 - 20%）、阿魏（阿魏 - A1 - 10%，A2 - 20%）、葡萄糖酸氯己定凝胶（洗必泰凝胶 - 1%）和氢氧化钙（10%）作为根管内药物对粪肠球菌的抗菌效果。
使用脑心浸液（BHI）琼脂制备琼脂平板。粪肠球菌培养物在37°C的BHI肉汤中生长。采用平板打孔法得出结果。平板在37°C接种72小时，记录微生物抑制圈。采用重复测量方差分析进行统计分析。
姜黄（T2 - 20%）和葡萄糖酸氯己定凝胶（洗必泰凝胶 - CHX - 1%）显示出比姜黄（T1 - 10%）更大的微生物抑制圈，具有统计学意义（P < 0.05），与阿魏（阿魏 - A1和A2）及氢氧化钙相比具有高度显著性。
姜黄可作为根管治疗失败病例的根管内药物。
