口腔癌患者总体健康与口腔健康相关生活质量之间的关联。
Association between general and oral health-related quality of life in patients treated for oral cancer.
作者信息
Barrios Rocío, Tsakos Georgios, Gil-Montoya José-Antonio, Montero Javier, Bravo Manuel
机构信息
C/ Campus Universitario Cartuja s/n, 18070, Granada, Spain,
出版信息
Med Oral Patol Oral Cir Bucal. 2015 Nov 1;20(6):e678-84. doi: 10.4317/medoral.20714.
BACKGROUND
Less is known about the association between general health-related quality of life (HRQoL) and oral HRQoL (OHRQoL) among patients with specific diseases. The aim of this study was to assess the association between patient-centered outcome measurements (HRQoL and OHRQoL) of oral cancer patients at least 6 months after treatment.
MATERIAL AND METHODS
HRQoL was measured with the 12-Item Short Form Health Survey (SF-12); OHRQoL was evaluated using the Oral Health Impact Profile (OHIP-14) and the Oral Impacts on Daily Performances (OIDP).
RESULTS
Higher OHRQoL scores were associated with lower SF-12 domains scores. The OHIP-14 explained 16.5 % of the total variance of SF-12 Physical Component Summary (PCS) and the OIDP explained 16.1 %. In the SF-12 Mental Component Summary (MCS), the total variance explained was 23.9 % by the OHIP-14 and 21.8 % by the OIDP.
CONCLUSIONS
There was a significant association between long-term OHRQoL and HRQoL in oral and oropharyngeal cancer patients. These results may help to carry out new interventions aiming to improve patient's life overall.
背景
关于特定疾病患者的总体健康相关生活质量（HRQoL）与口腔健康相关生活质量（OHRQoL）之间的关联，人们了解较少。本研究的目的是评估口腔癌患者治疗后至少6个月以患者为中心的结局指标（HRQoL和OHRQoL）之间的关联。
材料与方法
使用12项简短健康调查问卷（SF-12）测量HRQoL；使用口腔健康影响程度量表（OHIP-14）和口腔对日常表现的影响（OIDP）评估OHRQoL。
结果
较高的OHRQoL得分与较低的SF-12领域得分相关。OHIP-14解释了SF-12身体成分汇总（PCS）总方差的16.5%，OIDP解释了16.1%。在SF-12心理成分汇总（MCS）中，OHIP-14解释的总方差为23.9%，OIDP解释的为21.8%。
结论
口腔和口咽癌患者的长期OHRQoL与HRQoL之间存在显著关联。这些结果可能有助于开展旨在改善患者整体生活的新干预措施。
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