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三种药用植物抗菌活性的评估。

Evaluation of three medicinal plants for anti-microbial activity.

作者信息

Pratap Gowd M J S, Manoj Kumar M G, Sai Shankar A J, Sujatha B, Sreedevi E

机构信息

Assistant Professor, Department of Pedodontics and Preventive Dentistry, Sibar Institute of Dental Sciences, Guntur, Andhra Pradesh, India.

出版信息

Ayu. 2012 Jul;33(3):423-8. doi: 10.4103/0974-8520.108859.

Abstract

Herbal remedies have a long history of use for gum and tooth problems such as dental caries. The present microbiological study was carried out to evaluate the antimicrobial efficacy of three medicinal plants (Terminalia chebula Retz., Clitoria ternatea Linn., and Wedelia chinensis (Osbeck.) Merr.) on three pathogenic microorganisms in the oral cavity (Streptococcus mutans, Lactobacillus casei, and Staphylococcus aureus). Aqueous extract concentrations (5%, 10%, 25%, and 50%) were prepared from the fruits of Terminalia chebula, flowers of Clitoria ternatea, and leaves of Wedelia chinensis. The antimicrobial efficacy of the aqueous extract concentrations of each plant was tested using agar well diffusion method and the size of the inhibition zone was measured in millimeters. The results obtained showed that the diameter of zone of inhibition increased with increase in concentration of extract and the antimicrobial efficacy of the aqueous extracts of the three plants was observed in the increasing order - Wedelia chinensis < Clitoria ternatea < Terminalia chebula. It can be concluded that the tested extracts of all the three plants were effective against dental caries causing bacteria.

摘要

草药疗法用于治疗牙龈和牙齿问题(如龋齿)已有很长的历史。本微生物学研究旨在评估三种药用植物(诃子、蝶豆和蟛蜞菊)对口腔中的三种致病微生物(变形链球菌、干酪乳杆菌和金黄色葡萄球菌)的抗菌效果。分别从诃子的果实、蝶豆的花朵和蟛蜞菊的叶子制备了水提取物浓度(5%、10%、25%和50%)。使用琼脂扩散法测试每种植物水提取物浓度的抗菌效果,并以毫米为单位测量抑菌圈的大小。所得结果表明,抑菌圈直径随提取物浓度的增加而增大,且观察到三种植物水提取物的抗菌效果按以下顺序递增——蟛蜞菊<蝶豆<诃子。可以得出结论,所有三种植物的受试提取物对导致龋齿的细菌均有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c238/3665089/cb535dcb4edd/Ayu-33-423-g002.jpg

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