艾滋病患者伴急性水痘-带状疱疹病毒脑膜脊髓神经根炎时的脑脊液 HIV-1 分隔。
Cerebrospinal fluid HIV-1 compartmentalization in a patient with AIDS and acute varicella-zoster virus meningomyeloradiculitis.
机构信息
Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-1684, USA.
出版信息
Clin Infect Dis. 2013 Sep;57(5):e135-42. doi: 10.1093/cid/cit356. Epub 2013 May 31.
Abstract
We report a case of AIDS presenting as varicella-zoster virus (VZV) meningomyeloradiculitis associated with human immunodeficiency virus (HIV) quasispecies compartmentalization within the cerebrospinal fluid (CSF), and a CSF viral load that was 1 log higher than in peripheral blood. Prolonged antiviral therapy for both VZV and HIV type 1 was associated with partial resolution.
摘要
我们报告了一例艾滋病病例，表现为水痘带状疱疹病毒 (VZV) 脑膜脊髓神经根炎，与 HIV 准种在脑脊液 (CSF) 中的分隔有关，并且 CSF 中的病毒载量比外周血高 1 个对数。延长针对 VZV 和 HIV 1 型的抗病毒治疗与部分缓解有关。
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