Kim Eung-Du, Kim Jong Sung, Kim Sung-Soo, Jung Jin-Gyu, Yun Seok-Jun, Kim Ji-Young, Ryu Jung-Sun
Department of Family Medicine, Research Institute for Medical Sciences, Chungnam National University School of Medicine, Daejeon, Korea.
Korean J Fam Med. 2013 May;34(3):213-20. doi: 10.4082/kjfm.2013.34.3.213. Epub 2013 May 24.
Abdominal aortic calcification (AAC) is a marker of subclinical atherosclerotic disease and an independent predictor of subsequent vascular morbidity and mortality. This study was conducted to investigate the association of AAC with lifestyle and risk factors of cardiovascular disease.
The results of the abdominal computed tomography of 380 patients who visited Chungnam National University Hospital for a health checkup from January 1, 2008 to December 31, 2009 were reviewed. A six-point scale was used in grading the overall severity of the calcification in three areas of the abdominal aorta, including the area superior to the renal artery, the upper-half area inferior to the renal artery, and the lower-half area inferior to the renal artery, in addition to the common iliac artery. The association of the AAC severity with the age, lifestyle factors, and risk factors of cardiovascular disease was analyzed via multiple linear regression analysis.
In the male subjects, the age, presence of dyslipidemia and smoking were positively related to AAC, but exercising was negatively related to AAC (total R(2) = 0.563). In the female subjects, the age and presence of diabetes mellitus, hypertension, and dyslipidemia were positively related to AAC, but exercising was negatively related to AAC (total R(2) = 0.547).
AAC was related to both the male and female subjects' age, presence of dyslipidemia, and exercising, to smoking in the male subjects and to the presence of diabetes mellitus and hypertension in the female subjects.
腹主动脉钙化（AAC）是亚临床动脉粥样硬化疾病的一个标志物，也是后续血管发病和死亡的独立预测因子。本研究旨在调查AAC与生活方式及心血管疾病危险因素之间的关联。
回顾了2008年1月1日至2009年12月31日期间到忠南国立大学医院进行健康体检的380例患者的腹部计算机断层扫描结果。采用六点量表对腹主动脉三个区域（包括肾动脉上方区域、肾动脉下方上半区域、肾动脉下方下半区域）以及髂总动脉钙化的总体严重程度进行分级。通过多元线性回归分析AAC严重程度与年龄、生活方式因素及心血管疾病危险因素之间的关联。
在男性受试者中，年龄、血脂异常和吸烟与AAC呈正相关，但运动与AAC呈负相关（总R² = 0.563）。在女性受试者中，年龄、糖尿病、高血压和血脂异常与AAC呈正相关，但运动与AAC呈负相关（总R² = 0.547）。
AAC与男性和女性的年龄、血脂异常及运动有关，在男性中与吸烟有关，在女性中与糖尿病和高血压有关。
