Saxena Indu, Kumar Gaurav, Kumar Manoj, Kumar Jayballabh
Assistant Professor, Department of Biochemistry, Aiims Jodhpur, Rajasthan, India .
J Clin Diagn Res. 2013 Apr;7(4):635-7. doi: 10.7860/JCDR/2013/5430.2870. Epub 2013 Apr 1.
Low blood glucose levels have been associated with a hostile behaviour. The individuals who show aggressiveness and hostility are more likely to develop hypertension and cardiac diseases. The future hypertension has been linked with a high cardiovascular reactivity to stress. We have investigated the association of the blood glucose levels with the Cardio Vascular Reactivity (CVR) to stress.
Fourty six volunteers were subjected to stress (which was induced by the cold pressor task) in the fasting state and again, half an hour after the ingestion of 75 grams of glucose. The CVR in both conditions was compared in terms of an increase in the heart rate and the blood pressure.
The resting pulse was lower and the blood pressure was higher in the fasting condition, as compared to the values which were obtained in the ½ hour post-prandial condition. The CVR to stress was significantly higher in the fasting condition.
The increased resting heart rate and the decreased resting blood pressure in the ½ hourPost-Prandial (PP) condition was due to the higher levels of histamine in the post-prandial state. Low blood glucose levels are associated with a higher CVR to stress. This suggests that the persons are prone to develop future hypertension, those with frank hypertension, and the chronic pain sufferers should avoid prolonged fasts, in order to lower their CVR to the stress stimuli which are encountered in the daily life.
低血糖水平与攻击性行为有关。表现出攻击性和敌意的个体更易患高血压和心脏病。未来患高血压与对压力的高心血管反应性有关。我们研究了血糖水平与压力下心血管反应性（CVR）之间的关联。
46名志愿者在空腹状态下接受压力（由冷加压任务诱发），并在摄入75克葡萄糖半小时后再次接受压力。比较两种情况下心率和血压升高方面的CVR。
与餐后半小时状态下获得的值相比，空腹状态下静息脉搏较低，血压较高。空腹状态下对压力的CVR显著更高。
餐后半小时（PP）状态下静息心率增加和静息血压降低是由于餐后组胺水平较高。低血糖水平与对压力的较高CVR有关。这表明，为降低对日常生活中遇到的压力刺激的CVR，易患未来高血压的人、患有明显高血压的人以及慢性疼痛患者应避免长时间禁食。
