Yoshida Naohisa, Yagi Nobuaki, Inada Yutaka, Kugai Munehiro, Okayama Tetsuya, Kamada Kazuhiro, Katada Kazuhiro, Uchiyama Kazuhiko, Ishikawa Takeshi, Handa Osamu, Takagi Tomohisa, Konishi Hideyuki, Kokura Satoshi, Yanagisawa Akio, Naito Yuji
Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Dig Endosc. 2014 Mar;26(2):250-8. doi: 10.1111/den.12127. Epub 2013 Jun 3.
A new endoscope system with a laser light source, blue laser imaging (BLI), has been developed by Fujifilm that allows for narrow-band light observation. The aim of the present study was to evaluate the utility of BLI for the diagnosis of colorectal polyps.
We retrospectively analyzed 314 colorectal polyps that were examined with BLI observation at Kyoto Prefectural University of Medicine between September 2011 and January 2013. The surface and vascular patterns of polyps detected by published narrow-band imaging magnification: Hiroshima classification were used. Correlations were determined between the classifications and the histopathological diagnoses. Additionally, the ability of BLI without magnification to differentiate between neoplastic or non-neoplastic polyps was analyzed.
A total of 41 hyperplastic polyps, 168 adenomas, 80 intramucosal cancer, 11 shallowly invaded submucosal cancer, and 14 deeply invaded submucosal cancer were analyzed.Hyperplastic polyp was observed in 100% of Type A lesions (39 lesions), adenoma was observed in 89.3% of Type B lesions (159 lesions), intramucosal cancer and shallowly invaded submucosal cancer was observed in 69.6% of Type C1 (92 lesions) and in 84.6% of Type C2 (13 lesions), and deeply invaded submucosal cancer was observed in 81.8% of Type C3 lesions (11 lesions). The overall diagnostic accuracy of BLI with magnification was 84.3%. Additionally, the diagnostic accuracy of BLI without magnification for differentiating between neoplastic and non-neoplastic polyps <10 mm in diameter was 95.2%, which was greater than that of white light (83.2%).
BLI was useful for the diagnosis of colorectal polyps.
富士胶片公司研发了一种带有激光光源的新型内窥镜系统——蓝光激光成像（BLI），可实现窄带光观察。本研究旨在评估BLI在大肠息肉诊断中的应用价值。
我们回顾性分析了2011年9月至2013年1月间在京都府立医科大学接受BLI观察检查的314例大肠息肉。采用已发表的窄带成像放大：广岛分类法来观察息肉的表面和血管形态。确定分类与组织病理学诊断之间的相关性。此外，还分析了无放大功能的BLI区分肿瘤性或非肿瘤性息肉的能力。
共分析了41例增生性息肉、168例腺瘤、80例黏膜内癌、11例浅肌层浸润性癌和14例深肌层浸润性癌。在100%的A型病变（39例）中观察到增生性息肉，在89.3%的B型病变（159例）中观察到腺瘤，在69.6%的C1型（92例）和84.6%的C2型（13例）病变中观察到黏膜内癌和浅肌层浸润性癌，在81.8%的C3型病变（11例）中观察到深肌层浸润性癌。放大状态下BLI的总体诊断准确率为84.3%。此外，无放大功能的BLI区分直径<10 mm的肿瘤性和非肿瘤性息肉的诊断准确率为95.2%，高于白光（83.2%）。
BLI对大肠息肉的诊断有帮助。
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