Department of Infectious Diseases, Public Health Service, Amsterdam, the Netherlands.
Emerg Infect Dis. 2013 Jun;19(6):925-31. doi: 10.3201/eid1906.111864.
To assess the attack and incidence rates for influenza virus infections, during October 2006-October 2007 we prospectively studied 1,190 adult short-term travelers from the Netherlands to tropical and subtropical countries. Participants donated blood samples before and after travel and kept a travel diary. The samples were serologically tested for the epidemic strains during the study period. The attack rate for all infections was 7% (86 travelers) and for influenza-like illness (ILI), 0.8%. The incidence rate for all infections was 8.9 per 100 person-months and for ILI, 0.9%. Risk factors for infection were birth in a non-Western country, age 55-64 years, and ILI. In 15 travelers with fever or ILI, influenza virus infection was serologically confirmed; 7 of these travelers were considered contagious or incubating the infection while traveling home. Given the large number of travelers to (sub)tropical countries, travel-related infection most likely contributes to importation and further influenza spread worldwide.
为了评估流感病毒感染的发病和发生率，我们在 2006 年 10 月至 2007 年 10 月期间前瞻性地研究了 1190 名来自荷兰前往热带和亚热带国家的短期旅行者。参与者在旅行前后捐献了血样，并记录了旅行日记。在研究期间，对样本进行了血清学检测以确定流行株。所有感染的发病率为 7%（86 名旅行者），流感样疾病（ILI）的发病率为 0.8%。所有感染的发病率为每 100 人-月 8.9 例，ILI 的发病率为 0.9%。感染的危险因素包括出生在非西方国家、55-64 岁以及 ILI。在 15 名出现发热或 ILI 的旅行者中，经血清学确认为流感病毒感染；其中 7 名旅行者在旅行回家时被认为具有传染性或处于潜伏期。考虑到前往（亚）热带国家的旅行者人数众多，与旅行相关的感染很可能导致流感在全球范围内的输入和进一步传播。
