Graduate Program in Physical Education and Health, Catholic University of Brasília, Q.S. 07, lote 01, EPCT, Águas Claras, Taguatinga, Brasília, DF, CEP 71966-700, Brazil.
Aging Clin Exp Res. 2013 Apr;25(1):43-8. doi: 10.1007/s40520-013-0017-x. Epub 2013 Mar 27.
Whether intensity or other characteristics of physical activity can better promote the release of nitric oxide (NO) and reduction of blood pressure in hypertensive older-adults is still unknown. In this study, the post-exercise blood pressure (BP) response and NO release after different intensities of aerobic exercise in elderly women were analyzed.
Blood pressure response and NO were analyzed in 23 elderly mildly hypertensive women. Participants underwent (1) high-intensity incremental exercise (IT); (2) moderate-intensity 20 min exercise at 90% of the anaerobic threshold (AT), and (3) control (CONT) session. BP was measured before and after interventions; volunteers remained seated for 1 h. NO estimates were made through NO2- analyses.
After CONT session, both diastolic BP and mean arterial pressure (MAP) were significantly higher than during pre-exercise resting. Post-exercise hypotension (PEH) was observed after exercise at IT and 90% of AT. Although exercise in both sessions lowered SBP and MAP compared with CONT, exercise at the highest intensity (IT) was more effective on lowering systolic BP after exercise. In comparison with pre-exercise resting, NO2- increased significantly only after IT, but both exercise sessions caused NO2- to increase compared with CONT.
Exercise intensity and NO release may exert a role in eliciting PEH in mildly hypertensive elderly women.
高强度或其他特征的身体活动是否能更好地促进一氧化氮（NO）的释放和高血压老年患者血压的降低，目前尚不清楚。在这项研究中，分析了老年女性进行不同强度有氧运动后的运动后血压（BP）反应和 NO 释放。
对 23 名轻度高血压老年女性的血压反应和 NO 进行了分析。参与者进行了（1）高强度递增运动（IT）；（2）90%无氧阈（AT）的中等强度 20 分钟运动；（3）对照（CONT）。在干预前后测量血压；志愿者静坐 1 小时。通过 NO2-分析来估计 NO。
CONT 后，舒张压和平均动脉压（MAP）均明显高于运动前静息状态。IT 和 90%AT 运动后出现运动后低血压（PEH）。尽管两次运动均使 SBP 和 MAP 低于 CONT，但最高强度运动（IT）在运动后降低收缩压的效果更为显著。与运动前静息相比，仅在 IT 后 NO2- 显著增加，但与 CONT 相比，两次运动均使 NO2-增加。
运动强度和 NO 释放可能在诱发轻度高血压老年女性 PEH 中发挥作用。
