Hayes Peter, Ferrara Alexandra, Keating Aoife, McKnight Kathryn, O'Regan Andrew
School of Medicine, Health Research Institute, University of Limerick, V94 T9PX Limerick, Ireland.
Rev Cardiovasc Med. 2022 Sep 5;23(9):302. doi: 10.31083/j.rcm2309302. eCollection 2022 Sep.
Hypertension and physical inactivity are leading causes of premature mortality. While both are modifiable risk factors for cardiovascular disease, their prevalence remains high. As populations grow older, they are more likely to develop hypertension and to become less physically active. Scientific advances have contributed to understanding of how physical activity improves blood pressure and the clinically relevant ambulatory blood pressure, but this is not reflected in hypertension guidelines for clinical management of hypertension. The aim of this paper is to clearly present up to date knowledge from scientific studies that underpin the role of physical activity in hypertension management. Longitudinal studies in this review demonstrate a protective effect of higher physical activity levels as well as higher levels of cardiorespiratory fitness. Interventional studies report improvements in blood pressure associated with aerobic, resistance and concurrent exercise; the improvements in some studies were greatest among participant groups with established hypertensions; the effect was observed for groups with treatment-resistant hypertension also, a clinically important subgroup. The most recent research provides evidence for the synergy between physical activity and pharmacotherapy for the treatment of hypertension, providing an opportunity for clinicians to promote physical activity as an adjunctive treatment for hypertension as well as a preventative strategy. This review critiques the evidence and summarises the most up to date literature in the field of physical activity and hypertension.
高血压和缺乏身体活动是过早死亡的主要原因。虽然两者都是心血管疾病的可改变风险因素,但其患病率仍然很高。随着人口老龄化,他们更有可能患高血压且身体活动减少。科学进步有助于理解身体活动如何改善血压及临床上相关的动态血压,但这并未反映在高血压临床管理指南中。本文的目的是清晰呈现科学研究的最新知识,这些知识支撑了身体活动在高血压管理中的作用。本综述中的纵向研究表明,较高的身体活动水平以及较高的心肺适能具有保护作用。干预性研究报告了有氧运动、抗阻运动和联合运动与血压改善相关;在一些研究中,改善在已确诊高血压的参与者组中最为显著;在难治性高血压组(一个具有临床重要性的亚组)中也观察到了这种效果。最新研究为身体活动与药物治疗协同治疗高血压提供了证据,为临床医生提供了一个机会,可将身体活动作为高血压的辅助治疗方法以及预防策略来推广。本综述对相关证据进行了批判性分析,并总结了身体活动与高血压领域的最新文献。