El Meligy Omar A, Elemam Noha M, Talaat Iman M
Pediatric Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Alexandria University, Alexandria 21131, Egypt.
Dent J (Basel). 2023 Aug 7;11(8):187. doi: 10.3390/dj11080187.
Ozone has been successfully used in medicine for over 100 years due to its microbiological qualities. Its powerful oxidation impact, which results in the production of free radicals, and its ability to cause the direct death of nearly all microorganisms is the basis for its bactericide, virucide, and fungicide properties. Ozone also has a medicinal impact that speeds up blood flow and aids wound healing. Ozone may be applied as a gas or dissolved in water for medical purposes. Despite the benefits of using ozone therapeutically, concerns about its use in dentistry still exist. We aimed to provide a summary of the current uses of ozone in medicine and dentistry. An electronic search was performed for all English scientific papers published between 2012 and 2023 using PubMed, Cochrane, and Google Scholar search engines. Ozone, clinical applications, medicine, and dentistry were the search terms used. Seventy full-text articles describing the use of ozone therapy in medicine and dentistry were included in the present review. Ozone has shown several beneficial effects in the medical field. However, despite the encouraging in vitro evidence, the clinical use of ozone in dentistry has not yet been demonstrated as highly effective.
由于其微生物学特性，臭氧在医学领域已成功应用了100多年。其强大的氧化作用会产生自由基，并且能够直接导致几乎所有微生物死亡，这是其具备杀菌、杀病毒和杀真菌特性的基础。臭氧还具有促进血液循环和帮助伤口愈合的药用作用。臭氧可作为气体使用，也可溶解于水中用于医疗目的。尽管臭氧治疗有诸多益处，但在牙科领域对其使用仍存在担忧。我们旨在总结臭氧目前在医学和牙科领域的应用情况。使用PubMed、Cochrane和谷歌学术搜索引擎，对2012年至2023年间发表的所有英文科学论文进行了电子检索。检索词为臭氧、临床应用、医学和牙科。本综述纳入了70篇描述臭氧疗法在医学和牙科领域应用的全文文章。臭氧在医学领域已显示出多种有益效果。然而，尽管体外证据令人鼓舞，但臭氧在牙科的临床应用尚未被证明具有高效性。
