Paul F. Glenn Laboratories for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, USA.
Cell Stem Cell. 2013 Jun 6;12(6):641-3. doi: 10.1016/j.stem.2013.05.013.
Nonrandom chromosome segregation is an intriguing phenomenon linked to certain asymmetric stem cell divisions. In a recent report in Nature, Yadlapalli and Yamashita (2013) observe nonrandom segregation of X and Y chromosomes in Drosophila germline stem cells and shed light on the complex mechanisms of this fascinating process.
非随机染色体分离是与某些不对称干细胞分裂有关的有趣现象。在最近发表在《自然》杂志上的一篇报道中,Yadlapalli 和 Yamashita(2013 年)观察到果蝇生殖干细胞中 X 和 Y 染色体的非随机分离,并揭示了这一迷人过程的复杂机制。