State Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab), School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, PR China.
Analyst. 2013 Aug 21;138(16):4427-35. doi: 10.1039/c3an00438d. Epub 2013 Jun 10.
Recently, a growing amount of attention has been focused on the utility of biosensors for biomedical applications. Combined with nanomaterials and nanostructures, nano-scaled biosensors are installed for biomedical applications, such as pathogenic bacteria monitoring, virus recognition, disease biomarker detection, among others. These nano-biosensors offer a number of advantages and in many respects are ideally suited to biomedical applications, which could be made as extremely flexible devices, allowing biomedical analysis with speediness, excellent selectivity and high sensitivity. This minireview discusses the literature published in the latest years on the advances in biomedical applications of nano-scaled biosensors for disease bio-marking and detection, especially in bio-imaging and the diagnosis of pathological cells and viruses, monitoring pathogenic bacteria, thus providing insight into the future prospects of biosensors in relevant clinical applications.
近年来，人们越来越关注生物传感器在生物医学中的应用。将纳米材料和纳米结构与生物传感器相结合，可用于生物医学应用，例如病原体监测、病毒识别、疾病生物标志物检测等。这些纳米生物传感器具有许多优点，在许多方面非常适合生物医学应用，可以制成极其灵活的设备，实现快速、高选择性和高灵敏度的生物医学分析。本文综述了近年来关于纳米生物传感器在疾病生物标记物和检测中的生物医学应用的研究进展，特别是在生物成像以及对病理细胞和病毒的诊断、监测病原体方面的应用，为生物传感器在相关临床应用中的未来前景提供了新的见解。
