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Conserved regulatory elements in AMPK.

作者信息

Chen Lei, Xin Feng-Jiao, Wang Jue, Hu Jicheng, Zhang Yuan-Yuan, Wan Shuo, Cao Lu-Sha, Lu Chang, Li Peng, Yan S Frank, Neumann Dietbert, Schlattner Uwe, Xia Bin, Wang Zhi-Xin, Wu Jia-Wei

机构信息

MOE Key Laboratory of Protein Sciences and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

出版信息

Nature. 2013 Jun 13;498(7453):E8-10. doi: 10.1038/nature12189.

DOI:10.1038/nature12189
PMID:23765502
Abstract
摘要

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本文引用的文献

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AMP-activated protein kinase undergoes nucleotide-dependent conformational changes.腺苷酸活化蛋白激酶发生核苷酸依赖的构象变化。
Nat Struct Mol Biol. 2012 Jun 3;19(7):716-8. doi: 10.1038/nsmb.2319.
2
AMPK: a nutrient and energy sensor that maintains energy homeostasis.AMPK:一种营养和能量传感器,可维持能量平衡。
Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):251-62. doi: 10.1038/nrm3311.
3
AMPK functions as an adenylate charge-regulated protein kinase.AMPK 作为一种腺嘌呤核苷酸调控的蛋白激酶发挥作用。
Essays Biochem. 2024 Nov 18;68(3):321-336. doi: 10.1042/EBC20240007.
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Chemobiosis reveals tardigrade tun formation is dependent on reversible cysteine oxidation.化学生态揭示缓步动物的滞育形成依赖于半胱氨酸氧化的可逆性。
PLoS One. 2024 Jan 17;19(1):e0295062. doi: 10.1371/journal.pone.0295062. eCollection 2024.
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Overexpression of salusin‑β downregulates adipoR1 expression to prevent fatty acid oxidation in HepG2 cells.Salusin-β 的过表达下调脂联素受体 1 的表达,以防止 HepG2 细胞中的脂肪酸氧化。
Mol Med Rep. 2024 Feb;29(2). doi: 10.3892/mmr.2023.13141. Epub 2023 Dec 8.
6
AMPKα1 Deficiency in Astrocytes from a Rat Model of ALS Is Associated with an Altered Metabolic Resilience.星形胶质细胞中 AMPKα1 的缺失与 ALS 大鼠模型中的代谢弹性改变有关。
Biomolecules. 2023 Jul 28;13(8):1183. doi: 10.3390/biom13081183.
7
Metabolic and microbiota response to arginine supplementation and cyclic heat stress in broiler chickens.肉鸡对精氨酸补充和周期性热应激的代谢及微生物群反应。
Front Physiol. 2023 Mar 31;14:1155324. doi: 10.3389/fphys.2023.1155324. eCollection 2023.
8
Effect of Cyclic Heat Stress on Hypothalamic Oxygen Homeostasis and Inflammatory State in the Jungle Fowl and Three Broiler-Based Research Lines.循环热应激对原鸡及三个基于肉鸡的研究品系下丘脑氧稳态和炎症状态的影响
Front Vet Sci. 2022 May 25;9:905225. doi: 10.3389/fvets.2022.905225. eCollection 2022.
9
Chemotherapy Resistance: Role of Mitochondrial and Autophagic Components.化疗耐药性:线粒体和自噬成分的作用
Cancers (Basel). 2022 Mar 12;14(6):1462. doi: 10.3390/cancers14061462.
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AMPK-mTOR Signaling and Cellular Adaptations in Hypoxia.AMPK-mTOR 信号与低氧细胞适应性。
Int J Mol Sci. 2021 Sep 9;22(18):9765. doi: 10.3390/ijms22189765.
Trends Endocrinol Metab. 2012 Mar;23(3):125-32. doi: 10.1016/j.tem.2011.12.006. Epub 2012 Jan 26.
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AMP-activated protein kinase: also regulated by ADP?腺苷酸活化蛋白激酶:也受 ADP 调节?
Trends Biochem Sci. 2011 Sep;36(9):470-7. doi: 10.1016/j.tibs.2011.06.004. Epub 2011 Jul 23.
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Structure of mammalian AMPK and its regulation by ADP.哺乳动物 AMPK 的结构及其被 ADP 调节。
Nature. 2011 Apr 14;472(7342):230-3. doi: 10.1038/nature09932. Epub 2011 Mar 13.
6
β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).β-亚基豆蔻酰化是 AMP 激活的蛋白激酶(AMPK)启动代谢应激感应的守门员。
Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19237-41. doi: 10.1073/pnas.1009705107. Epub 2010 Oct 25.
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Structural insight into the autoinhibition mechanism of AMP-activated protein kinase.对AMP激活的蛋白激酶自抑制机制的结构洞察
Nature. 2009 Jun 25;459(7250):1146-9. doi: 10.1038/nature08075. Epub 2009 May 27.
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