School of Chemistry, University of Glasgow, G12 8QQ, United Kingdom.
Beilstein J Nanotechnol. 2013 Apr 29;4:285-91. doi: 10.3762/bjnano.4.31. Print 2013.
Herein, we present an approach for the rapid, straightforward and economical preparation of a tailored reactor device using three-dimensional (3D) printing, which can be directly linked to a high-resolution electrospray ionisation mass spectrometer (ESI-MS) for real-time, in-line observations. To highlight the potential of the setup, supramolecular coordination chemistry was carried out in the device, with the product of the reactions being recorded continuously and in parallel by ESI-MS. Utilising in-house-programmed computer control, the reactant flow rates and order were carefully controlled and varied, with the changes in the pump inlets being mirrored by the recorded ESI-MS spectra.
在此，我们提出了一种使用三维（3D）打印快速、直接和经济地制备定制反应器装置的方法，该装置可以直接与高分辨率电喷雾电离质谱（ESI-MS）连接，用于实时在线观察。为了突出该装置的潜力，在该装置中进行了超分子配位化学实验，ESI-MS 连续平行地记录反应产物。利用内部编写的计算机控制程序，仔细控制和改变反应物的流速和顺序，通过记录的 ESI-MS 谱图反映泵入口的变化。
