State Key Laboratory of Organometallic Chemistry, Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Angew Chem Int Ed Engl. 2013 Jul 15;52(29):7549-53. doi: 10.1002/anie.201301891. Epub 2013 Jun 14.
Group activity: A novel copper-catalyzed fluorination of internal allylic bromides and chlorides has been developed by using Et3N⋅3 HF as the fluorine source. A functional group (FG) within the substrate is required to achieve the allylic fluorination, and a variety of secondary allylic fluoride compounds can be accessed in good yield with excellent regioselectivity.
通过使用 Et3N⋅3HF 作为氟源，开发了一种新型的铜催化内部烯丙基溴化物和氯化物的氟化反应。底物中的一个官能团 (FG) 是实现烯丙基氟化所必需的，并且可以以优异的区域选择性获得各种高产率的仲烯丙基氟化物化合物。
