Department of Ophthalmology, St Thomas' Hospital, London, UK.
Eye (Lond). 2013 Sep;27(9):1063-9. doi: 10.1038/eye.2013.136. Epub 2013 Jun 21.
To examine pre-operative characteristics of rhegmatogenous retinal detachment (RRD) and their relationship to visual acuity (VA) following surgery.
Review of prospectively completed electronic database. Baseline characteristics, retinal drawings and outcomes were analysed.
In all, 847 eyes from 847 patients with a mean age of 62.2 years, 60% males, and 56% right eyes were studied. Mean follow-up was 9.6 months. Preoperative VA correlated with final VA (r(2)=0.21, P<0.0001). Median postoperative VA was 6/9 (Logmar 0.18, quartiles=0.0-0.48) and was significantly related to anatomical success: 70.15% achieved 0.18 or better with fully attached retina and primary success, whereas only 8.33% achieved this when the retina was not fully attached at final follow-up (failure) (P<0.0001). Univariate analysis found multiple variables associated with achieving 0.18 postoperative vision, however, multivariate analysis revealed only primary anatomical success with surgery; absence of proliferative vitreo-retinopathy (PVR), better-presenting VA and fewer quadrants of detachment were associated with a better visual outcome (r(2)=0.26, P<0.0001). Patients with a clinically attached fovea achieved better vision than patients with a clinically detached fovea, independent of the visual loss duration. With foveal detachment however, postoperative VA was better in patients with 1-3 days of visual loss compared with 4-6 days (P=0.013).
Failure of primary surgery, PVR, extensive RRD and poor-presenting VA are risk factors for poorer visual outcome following surgery for RRD. Fovea off RRD at presentation achieved poorer postoperative VA than fovea attached and visual outcome was poorer when there was a longer duration of visual symptoms.
探讨孔源性视网膜脱离(RRD)术前特征及其与术后视力(VA)的关系。
回顾性分析前瞻性电子数据库。分析基线特征、视网膜图和结果。
共纳入 847 只眼(847 例患者),平均年龄 62.2 岁,男性占 60%,右眼占 56%。平均随访时间为 9.6 个月。术前 VA 与最终 VA 相关(r²=0.21,P<0.0001)。术后中位数 VA 为 6/9(LogMAR 0.18,四分位数=0.0-0.48),与解剖学成功显著相关:完全贴附视网膜和初次成功的患者中,70.15%达到 0.18 或更好,而在最终随访时视网膜未完全贴附(失败)的患者中,只有 8.33%达到这一水平(P<0.0001)。单变量分析发现多个变量与术后 0.18 视力有关,但多变量分析显示,只有手术的初次解剖成功;无增生性玻璃体视网膜病变(PVR)、更好的 VA 表现和较少的象限脱离与更好的视力结果相关(r²=0.26,P<0.0001)。临床附着的黄斑区较临床脱离的黄斑区视力更好,而与视力丧失时间无关。然而,在黄斑区脱离的情况下,与 4-6 天的视力丧失相比,1-3 天的视力丧失患者术后 VA 更好(P=0.013)。
初次手术失败、PVR、广泛的 RRD 和较差的 VA 表现是 RRD 手术后视力不良的危险因素。与黄斑区附着的 RRD 相比,黄斑区脱离时,术后 VA 较差,且症状持续时间越长,视力预后越差。