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用富血小板纤维蛋白胶成功治疗先天性乳糜腹。

Successful treatment of congenital chyloperitoneum with platelet-rich fibrin glue.

作者信息

Joudi Marjan, Alamdari Daryoush Hamidi, Rahimi Hamid-Reza

机构信息

Surgical Oncology research center, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Iran J Pediatr. 2013 Jun;23(3):357-9.

Abstract

BACKGROUND

Congenital chyloperitoneum is an uncommon clinical condition. A few cases of congenital chyloperitoneum in children have been described who were treated in a variety of methods.

CASE PRESENTATION

Congenital chyloperito was diagnosed in a 5-day-old baby boy with a significant abdominal distension. Due to the failed conservative managements by medium-chain triglycerides (MCT) enriched milk and partial parenteral nutrition (PPN), the authors tried platelet rich fibrin glue (PRFG) as an alternative choice which was applied through an already inserted intra-abdominal catheter. PRFG successfully stopped the lymph leakage from all over the small intestinal mesentery; thereby PRFG may be considered as an effective alternative treatment before surgical intervention.

CONCLUSION

Applying PRFG is an easy, safe, and effective alternative option that may be used to close the chylous ascites lymph leakage in children if conservative management with PPN fails.

摘要

背景

先天性乳糜腹是一种罕见的临床病症。已有少数儿童先天性乳糜腹病例的报道,其治疗方法多样。

病例介绍

一名5天大的男婴因明显腹胀被诊断为先天性乳糜腹。由于采用富含中链甘油三酯(MCT)的牛奶及部分肠外营养(PPN)进行保守治疗失败,作者尝试将富血小板纤维蛋白胶(PRFG)作为替代选择,通过已插入的腹腔导管应用。PRFG成功止住了来自小肠系膜各处的淋巴漏;因此,在手术干预前,PRFG可被视为一种有效的替代治疗方法。

结论

如果PPN保守治疗失败,应用PRFG是一种简便、安全且有效的替代选择,可用于闭合儿童乳糜性腹水的淋巴漏。

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Refractory congenital chylous ascites.难治性先天性乳糜性腹水
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Fibrin glues of human origin.人源纤维蛋白胶。
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