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日本大阪基于人群癌症登记数据的 2000-2004 年长期生存者的条件生存。

Conditional survival for longer-term survivors from 2000-2004 using population-based cancer registry data in Osaka, Japan.

机构信息

Center for Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka, Japan.

出版信息

BMC Cancer. 2013 Jun 22;13:304. doi: 10.1186/1471-2407-13-304.

Abstract

BACKGROUND

We usually report five-year survival from population-based cancer registries in Japan; however these survival estimates may be pessimistic for cancer survivors, because many patients with unfavourable prognosis die shortly after diagnosis. Conditional survival can provide relevant information for cancer survivors, their family and oncologists.

METHODS

We used the period approach to estimate the latest 10-year survival of 38,439 patients with stomach, colorectal, lung, breast and prostate cancer diagnosed between 1990 and 2004 and followed-up from 2000-04 in Osaka, Japan. Conditional survival is an estimate, with the pre-condition of having already survived a certain length of time. Conditional five-year relative survival of one to five years after diagnosis was calculated by site, age and stage for survivors under the age of 70.

RESULTS

Five-year relative survival for stomach cancer was 60%. Conditional five-year relative survival was 77% one year after diagnosis and 97% five years after diagnosis. This means that 97% of patients who survive five years after diagnosis can survive a further five years. Conditional five-year relative survival improved successively with each additional year that patients lived after diagnosis for stomach, colorectal and lung cancer. These figures for breast and prostate cancer were stable at high survival. Liver cancer did not show an increase in conditional five-year survival.

CONCLUSION

Conditional five-year survival is a relevant figure for long-term cancer survivors in Japan. It is important for population-based cancer registries to provide figures which cancer patients and oncologists really need.

摘要

背景

我们通常会根据日本的人口癌症登记报告五年生存率;然而,这些生存估计可能对癌症幸存者来说过于悲观,因为许多预后不良的患者在确诊后不久就去世了。条件生存可以为癌症幸存者、他们的家人和肿瘤医生提供相关信息。

方法

我们使用期间法估计了 1990 年至 2004 年间诊断、2000-04 年随访的 38439 例胃癌、结直肠癌、肺癌、乳腺癌和前列腺癌患者的最新 10 年生存情况。条件生存是一种估计,其前提是已经生存了一定的时间。对于年龄在 70 岁以下的幸存者,按部位、年龄和分期计算了诊断后 1-5 年的条件五年相对生存率。

结果

胃癌的五年相对生存率为 60%。诊断后一年的条件五年相对生存率为 77%,五年后为 97%。这意味着诊断后五年存活的患者中有 97%可以再存活五年。对于胃癌、结直肠癌和肺癌,随着患者在诊断后存活的时间增加,条件五年相对生存率依次提高。乳腺癌和前列腺癌的这些数据在高生存率下保持稳定。肝癌的条件五年生存率没有增加。

结论

条件五年生存率是日本长期癌症幸存者的一个相关指标。为癌症患者和肿瘤医生提供他们真正需要的数字对基于人群的癌症登记非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/239f/3701478/23886e3903a5/1471-2407-13-304-1.jpg

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